Module 3: Olfaction Flashcards
where do olfactory nerves project to
olfactory bulb
which nerve connects olfactory nerves to the olfactory bulb
olfactory nerve (CNI)
where do olfactory bulbs project to
olfactory bulb targets: piriform cortex, olfactory tubercle, amygdala, entorhinal cortex
where does piriform cortex project to
orbitofrontal cortex
where do the olfactory tubercle, amygdala, and entorhinal cortex project to
orbitofrontal cortex, thalamus, hypothalamus
where does entorhinal cortex project to (unique)
hippocampal formation
what do the amygdala and hypothalamus influence
motor, visceral, and emotional reactions to stimuli relevant to feeding, reproduction, and aggression
what do taste receptor cells develop from
epithelial cells
what do olfactory cells develop from
neurons
stem cell function in olfaction
renew olfactory sensors every few weeks
what does the nasal cavity contain
respiratory epithelium and olfactory epithelium
what does the influx of Na+, Ca2+, and efflux of Cl- cause
membrane depolarization (receptor potential) in the cilia
what happens if the receptor potential is high enough
it propogates to the dendrite and triggers series of AP in soma
does olfactory system use labeled line coding
no
what coding does olfactory system use
population coding
how does population coding work
- each receptor cell expresses one OR protein
- different receptor cells are scattered within OE
- each cell responds to different odors with different preferences
what is a glomerulus
the point where about 25000 olfactory receptor cells and about 100 second-order olfactory neurons synapse
how many glomeruli are in the input layer of the bulb
2000
what are mitral and tufted cells excited by
inputs from OSN
how does olfactory sensitivity change over time
it is gradually reduced
what do periglomular and granule cells do
modulate activity of mitral and tufted cells
