Module 3 - Immunity Flashcards
Where do B cells mature?
Bone Marrow
Where do T cells mature?
Thymus
Define Immunity
The body’s specific protective response to a foreign agent or organism.
ex. HIV/AIDS, Hypersensitivity, RA
Define Autoimmunity
Normal protective immune response paradoxically turns against or attacks the body, leading to tissue damage.
Define Hypersensitivity
Body produces inappropriate or exaggerated responses to specific antigens.
Define Gammopathies
Overproduction of immunoglobulins.
Define Immune deficiencies primary
Deficiency results from improper development of immune cells or tissues; usually congential or inherited.
Define Immune deficiencies secondary
Deficiency results from some interference with an already developed immune system; usually acquired later in life.
Two components of the immune system
- Bone marrow which include WBC production and T Cells and B cells.
- Lymphoid Tissue which includes spleen and lymph nodes
Define Natural Immunity
Nonspecific response to a foreign invader, no prior exposure to foreign substance.
-considered the first line of host defense
Define Acquired Immunity
Specific response against a foreign invader, a result of prior exposure to antigen
Can be active or passive
Example: Vaccines
Physical Barriers to foreign invaders
Intact skin
Chemical Barriers to foreign invaders
Acidic gastric secretions
Enzymes in tears and saliva
1st Line of Defense to foreign invaders and largest organ
Intact Skin
Humoral immunity (antibody protection)
Lymphocytes: B cells
Secrete antibodies to viruses and bacteria
Recognize antigens
Antibodies Mark the antigen for cell destruction
Do not destroy the foreign cell
Crosses the placenta in the form of IgG