Module 3 Flashcards
Food nourishes the body by supplying necessary nutrients and calories to function in:
- to provide energy for necessary activities
- to build and maintain body tissues
- To regulate body processes
Nutrients necessary to the body
- macronutrients
- micronutrients
- water
stimulates the pituitary to release growth hormone
Growth hormone-releasing hormone (GHRH)
Other name for growth hormone–inhibiting hormone (GHIBH)
Somatostatin
inhibits the secretion of both GHRH and thyroid- stimulating hormone (TSH)
Somatostatin or growth hormone-inhibiting hormone (GHIBH)
_________ hormone is secreted in pulses
Growth
70% of this hormone secretion occurs during deep sleep
Growth Hormone
regulates carbohydrate, protein, and lipid metabolism
Growth hormone
Stimulates growth hormone secretion
Thyroid hormone
Thyroid hormone stimulates production of
insulin-like growth factor 1 (IGF-1) and interleukins 6 and 8 (IL-6 and IL-8)
T or F: growth hormone also affects the growth and maturation of other body tissues.
F; the thyroid hormone does that
is a type of growth hormone produced by the liver and in peripheral tissues, like bone
IGF-1
________ releases growth hormone releasing hormone (GHRH)
Hypothalamus
GHRH stimulates _________ to release growth hormone
anterior pituitary
_______ exerts a negative feedback effect on growth hormone secretion and mediates the effect of growth hormone on bone, muscle, nervous system, and immune system cells
IGF-1
What is Ghrelin
A peptide
Known as the Hunger hormone
Ghrelin
helps control growth hormone release and influences food intake and obesity development
Ghrelin
has a key role in regulating body fat mass, and its concentration is thought to be a trigger for puberty by informing the central nervous system that adequate nutritional status and body fat mass are present to support pubertal changes and growth
Leptin
During puberty, with an increase in leptin, a relative _________ in fat percentage develops in males and an ____________ occurs in female
Decrease; increase
What do the gonads secrete during puberty
Testosterone and estrogen
Rising levels of testosterone and estrogen release what
Gonadotropins (lutenizing hormone (LH) and follicle-stimulating hormone (FSH)
Where do luteinizing hormone and follicle stimulating hormone release from
Hypothalamus
_________________ enhances muscular development and sexual maturation and promotes bone maturation and epiphyseal closure
Testosterone
stimulates the development of female secondary sexual characteristics, regulating the timing of the growth spurt and the acceleration of skeletal maturation and epiphyseal fusion.
Estrogen
Androgens are secreted by
Adrenal glands
promote masculinization manifested by secondary sex characteristics and skeletal maturation.
Androgens
Growth at puberty is dependent on the interaction of which hormones
- Growth hormone
- IGF-1
- Leptin
- Androgens (sex steroids)
What leads to adolescent growth spurt
The sex steroids stimulate an increased secretion of growth hormone, which in turn mediates the dramatic increase in IGF-1
Skeletal growth is considered complete when
epiphyses of long bones have completely fused during late puberty
More than ___% of the skeletal mass is present by 18 years of age
90
Examples of lymphatic tissues
- adenoids
- blood lymphocytes
- lymph nodes
- spleen
- tonsils
T or F: Lymphatic tissues are well developed at birth
True
Lymphatic tissues reach adult size at about ______ years old
6
What happens to lymphatic tissues between ages 6 and 20
Adult size by 6
Age 10-12 about double the adult size
During adolescence they decrease to adult size
… complete physical development more quickly than other body parts
Brain, skull , eyes, ears
Time period of most rapid and critical brain growth
Conception and 3 years of age
By 34 weeks’ gestation, ____% of the weight of a newborn’s brain is present
65
Gray matter and myelinated white matter increase dramatically between the _____ and ______ weeks of gestation
34th and 40th
In the nervous system, _______, ______, and _______ continue to develop after birth
Glial cells, dendrites, and myelin
Why does the head size increase in adolescents
Development of air sinuses and the thickening of the scalp and skull
is influenced by genetic predisposition, gestational age, the mother’s prepregnancy weight, weight gain during pregnancy, environmental exposures like secondhand smoke, overall maternal health, and intercurrent disease or complications in pregnancy such as gestational diabetes.
Birth weight
Fastest growing body part in infancy
Trunk
Fastest growing body part during childhood
Legs
During adolescence, about _____% of the individual’s ideal weight is gained, and the skeletal mass and organ systems_______ in size.
50; double
Most weight is lost postpartum in first _______ months after delivery
3
Preschool aged children should engage in about _____ hours of activity a day
3
Children 6-17 years of age should engage in _______ minutes of activity a day
60
People 18-64 should engage in ________ of activity a week
150 minutes of moderate intensity or 75 minutes of vigorous activity
Method for obtaining a food intake history
24-hour recall
Five nutrients may be deficient in a vegetarian diet
- Protein
- Calcium (lacto-ovo and vegan)
- Iron
- Vitamin B12 (vegan)
- Vitamin D
Healthy BMI range
18.5-24.9
BMI of greater than _______ is indicative of obesity
30
are indicators of visceral fat or abdominal obesity
Waist circumference and waist-height ratio
At birth, healthy term newborns have length variations between _____________ inches
18-22 (45-55 cm)
Infant body length increases by ________ in the first year of life
50%
After losing up to 10% of their birth weight, newborns regain that weight within 2 weeks and then gain weight at a rate of approximately _________ per day
30 g (1 oz)
Infants lose about _______% of their birthweight
10
Expected head circumferences for term newborns range between ____________
32.5 and 37.5 cm
By what age should a child’s head circumference be 2/3 its adult size
2 years old
evaluates six physical and six neuromuscular newborn characteristics within 36 hours of birth to establish or confirm the newborn’s gestational age
The Ballard Gestational Age Assessment Tool
The gestational ages of _______through _____ weeks are considered term and are associated with the best health outcomes
37 through 42
In a child, arm span that exceeds height is associated with
Marfan syndrome
A higher upper-to-lower body segment ratio than expected may be associated with
dwarfism or bone disorders
Approximately _______% of women are obese
42.4-43.3%
A rare disease of excessive growth and distorted proportions caused by hypersecretion of growth hormone and insulin-like growth factor after closure of the epiphyses
Acromegaly
Most commonly caused by the use of medically prescribed corticosteroids.
Cushing syndrome
causes include adrenal gland oversecretion leading to excessive production of cortisol or a pituitary tumor leading to excessive secretion of adrenocorticotropic hormone (ACTH)
Cushing syndrome
A genetic disorder in which there is partial or complete absence of a second X chromosome
Turner syndrome
Phenotype results from a reduced complement of genes that are typically expressed from both X chromosomes in females.
Turner syndrome
Turner syndrome incidence is 1 per______ live birth
2500–3000
May be caused by an infection or obstruction in the subarachnoid space that interferes with the reabsorption of CSF, or from an infection or injury that obstructs the flow of CSF to the subarachnoid space where it can be reabsorbed.
Hydrocephalus
An excess volume of cerebrospinal fluid (CSF) in the brain leading to an enlarged head circumference or increased intracranial pressure
Hydrocephalus
Often occurs in association with meningomyelocele
Hydrocephalus
Growth in an infant or child below the third to fifth percentiles on a growth chart, or a slower than expected rate of growth or crossing down two percentile lines in a short period of time (e.g., from the 50th percentile to below the 10th percentile on the growth chart)
Failure to thrive
Failure of the anterior pituitary to secrete adequate growth hormone to support growth in stature
Growth hormone deficeincy
May be congenital or develop from a pituitary tumor, radiation therapy for a tumor, or brain trauma
Growth hormone deficiency
The onset of secondary sexual characteristics before 7 years of age in white females, 6 years in Black females, and 9 years of age in males with progressive sexual maturation
Precocious puberty
A brain tumor or lesion (e.g., hypothalamic hamartoma) may activate the hypothalamic- pituitary-gonadal axis with gonadotropins triggering the growth of the gonads, secretion of the sex hormones, and progressive sexual maturation.
Precocious Puberty
May also be related to McCune-Albright syndrome
Precocious puberty
Excessive proportion of total body fat
Obesity
Eating disorder classified by the Diagnostic and Statistical Manual of Mental Disorders (fifth edition; DSM-V) as a psychiatric disease, characterized by low body weight and body image distortion
Anorexia nerovosa
Two types of anorexia
Purging and restricting
Eating disorder with two types: purging and nonpurging type episodes followed by fasting or excessive exercising
Bulimia nervosa
T or F: anatomy of the skin remains the same from one part of the body to another
False: anatomy varies from one part to the other
The outermost portion of the skin that is composed of several cellular layers
Epidermis
The top most layer of the epidermis
Stratum corneum (cornified layer)
Composed of closely packed, dead, keratin-filled squamous cells
Stratum corneum of the epidermis
Chief mechanical barrier protecting the body against environmental exposures, pathogens, and restricting water loss
Stratum corneum
Where are the keratins of the stratum corneum synthesized
Beginning at the stratum basale (basal layer)
The lower layers contain _________, which allow for the regenerative properties of the skin to manifest
Stem cells
As keratinocytes mature, they pass from the ________ layer through the _________ layer to the cornified layer
Basal, granular
As keratinocytes mature, they pass from the basal layer through the granular layer to the cornified layer— how long does this process take?
28 days
The thick skin of the palms and soles contains an additional layer compared with other parts of the body called the ________________
stratum lucidum
Where is the stratum lucidem (of thick skin on palms and soles of feet) beneath
The stratum corneum
Mucosal skin lacks:
Stratum corneum
Where are melanocytes located
Stratum basale
richly vascular connective tissue layer of the skin that supports and separates the epidermis from adipose tissue
Dermis
secure the epidermis to the dermis and provide nourishment to the epidermal cells
Interdigitating papillae
provide resilience, strength, and stability in the dermis
- elastin
- collagen
- reticular fibers
Sensory nerve fibers located in the _________ form a complex network that provides sensations of pain, touch, and temperature.
Dermis
contains autonomic motor nerves that innervate blood vessels, glands, and the arrector pili muscles
Dermis
The dermis is connected to underlying tissues by the
Hypodermis
a subcutaneous layer that consists of loose connective tissue filled with adipose
Hypodermis
Generates heat, provides insulation, shock absorption, and calorie reserve
Adipose layer of the hypodermis
are outgrowths of the skin and include eccrine sweat glands, apocrine sweat glands, sebaceous glands, hair, and nails
Cutaneous appendages
open directly onto the surface of the skin and help regulate body temperature through sweat secretion.
Eccrine sweat glands
These glands are distributed throughout the body except at the lip margins, eardrums, nail beds, inner surface of the prepuce, and glans penis
Eccrine sweat glands
Type of glands found only in the axillae, nipples, areolae, anogenital area, eyelids, and external ears
Apocrine glands
secrete an oily fluid containing protein, carbohydrate, and other substances that are odorless
Apocrine glands
How is body odor produced
By bacterial decomposition of apocrine sweat
a lipid-rich substance that acts as a lubricant and moisturizer for skin and hair
Sebum
__________ secretes sebum
Sebaceous glands
Secretory activity of sebum is stimulated by
Sex hormones, primarily testosterone
A strand of hair consists of a root and a shaft which sit in a _________
Follicle
What supplies nourishment and growth to a hair follicle
Papilla contains loop of capillaries
What gives hair its color
Melanocytes in the follicle synthesize pigment
Adults have both ________ and ________ hair.
Vellus; terminal
hair that is short, fine, soft, and nonpigmented
Vellus
Hair that is coarser, longer, thicker, and usually pigmented
Terminal hair
Cycles of Hair growth
Anagen (growth)
Catagen (atrophy)
Telogen (rest)
Exogen (Hair is shed)
Infants and children lack which type of hair
Terminal hair
a mixture of sebum and cornified epidermis, covers the infant’s body at birth
Vernix Caseosa
The newborn’s body, particularly the shoulders and back, can be covered with fine, silky hair called
Lanugo
Lanugo in neonates is typically shed in how many days
10-14 days
T or F: lanugo is more commonly seen in preterm infants
True
When do eccrine sweat glands develop
First month of life
When do apocrine glands form in children
Puberty
T or F: Children lack offensive perspiration
True because they do not have apocrine function until puberty
Hair production is one response to changing ________levels
Androgen
Processes that assists in dissipating the excess heat caused by increased metabolism in pregnancy
Acceleration of sweat/sebaceous gland activity and increased blood flow to skin (from peripheral dilation and increased number of capillaries)
In pregnancy, the skin thickens and fat is deposited in the ______ layers
Subdermal
T or F: sweat activity increases in older adults
F it decreases
What causes the skin to wrinkle in older adults
The dermis shrinks causing epidermis to fold
They are most commonly seen on the arms, legs, chest, and back and have been reported most often in Black and Japanese populations
Pigmentary demarcation lines
There is a strong association between sun exposure and the number of ______
Nevi
Spider Angiomas are
A. Arterial
B. Venous
Arterial
permanently dilated blood vessels consisting of venules or arterioles.
Telangiectasias: spider angioma
is a handheld magnifying lens that is useful in evaluating the subtle details of a lesion by providing polarized light to allow for visualization of deeper skin structures and non-polarized light for the assessment of superficial skin lesions.
Dermatoscope
Dryness and brittleness of scalp hair could indicate
Systemic or genetic disorder
Hirsutism in women, growth of terminal hair in a male distribution pattern on face, body and pubic are, could signify an _________
Endocrine disorder
A flat, circumscribed area that is a change in the color of the skin; less than 1 cm in diameter
Macule
An elevated, firm, circumscribed area; less than 1 cm in diameter
Papule
A flat, nonpalpable, irregularly shaped macule greater than 1 cm in diameter
Patch
Freckles, flat nevi, petechiae are examples of …
Macule
Warts (verruca), and lichen planus are examples of
Papule
Vitiligo, port-wine stains, cafe au lair patch are examples of
Patch
Psoriases, atopic dermatitis are examples of
Plaques
Elevated, firm, and rough
lesion with flat top surface greater than 1 cm in diameter
Plaques
Elevated, irregular- shaped area of cutaneous edema; solid, transient, variable diameter
Wheal
Elevated, firm, circumscribed lesion; deeper in dermis than a papule; 1–2 cm in diameter
Nodule
Insect bites, urticaria, and allergic reactions are examples of
Wheal
Elevated and solid lesion; may or may
not be clearly demarcated; deeper in dermis; greater than 2 cm in diameter
Tumor
Neoplasms, benign tumor, lipoma are examples of
Tumors
Elevated, circumscribed, superficial, not into dermis; filled with serous fluid; less than 1 cm in diameter
Vesicles
Varicella (chickenpox), herpes zoster (shingles) are what type of skin lesion
Vesicles
Vesicle greater than 1 cm in diameter
Bulla
Bullous pemphigus, pemphigus vulgaris are examples of what kind of skin abnormality
Bulla
Elevated, superficial lesion; similar to a vesicle but filled with purulent fluid
Pustule
Impetigo and acne are examples of what kind of skin abnormality
Pustules
Elevated, circumscribed, encapsulated lesion; in dermis or subcutaneous layer; filled with liquid or semisolid material
Cyst
Fine, irregular, red lines produced by capillary dilation
Telangiectasia
What kind of skin abnormality would you see Telangiectasia
Rosacea
Heaped-up, keratinized cells; flaky skin; irregular; thick or thin; dry or oily; variation in size
Scale
Rough, thickened epidermis secondary to persistent rubbing, itching, or skin irritation; often involves flexor surface of extremity
Lichenification
Chronic atopic dermatitis is an example of what skin abnormality
Lichenification
Irregularly shaped, elevated, progressively enlarging scar; grows beyond the boundaries of the wound; caused by excessive collagen formation during healing
Keloid
Thin to thick fibrous tissue that replaces normal skin after injury or laceration to the dermis
Scar
Loss of the epidermis; linear hollowed- out, crusted area
Excoriation
Linear crack or break from the epidermis to the dermis; may be moist or dry
Fissure
Example of a fissure
Athletes foot
Loss of part of the epidermis; depressed, moist, glistening; follows rupture of a vesicle or bulla
Erosion
Loss of epidermis and dermis; concave; varies in size
Ulcer
Thinning of skin surface and loss of skin markings; skin translucent and paper- like
Atrophy
Ragged cuticles are also a classic sign of
Dermatomyositis
Peeling nails (from the plate splitting into layers) usually found in
- hands repeated water immersion
- have underlying psoriasis
Causes of yellow discoloration of nails
- psoriasis
- fungal infections
- chronic respiratory diseases
Proximal subungual fungal infection is associated with
HIV infection
A complete absence of a nail
Anonychia
The ___________ method is when a patient places together the nail (dorsal) surfaces of the thumbs from both the right and left hands and is used to assess for clubbing
Schamroth
Expected skin finding in newborn: Cyanosis of hands and feet
Acrocyanosis
Expected skin finding in newborn: Transient mottling when infant is exposed to decreased temperature
Cutis marmorata
Expected skin finding the newborn: Pink papular rash with vesicles superimposed on thorax, back, buttocks, and abdomen; may appear in 24-48 hr and resolve after several days
Erythema toxicum
Expected skins change in a newborn: Irregular areas of deep blue pigmentation, usually in the sacral and gluteal regions; seen predominantly in newborns of African, Native American/American Indian, Asian, or Latin descent
Congenital dermal melanocytosis
Expected skin changes in a newborn: Flat, deep pink localized areas usually seen on the midforehead, eyelids, upper lip, and back of neck
Nevis simplex