Module 1.3 (Enzymes) Flashcards
_____ are key to life.
no ____ no life
enzymes
globular protein which functions as a biological catalyst, speeding up reaction rate by lowering activation energy without being affected by the reaction it catalyze
enzymes
- are protein in nature (globular protein)
- are composed of long chains of amino acids that have folded into a very specific three-dimensional shape which contains an active site.
enzymes
are RNA molecule with enzymatic activity
Ribozymes
Catalytic behaviour of any enzyme depends upon its _________________ (4)
primary, secondary, tertiary or quaternary structure
Enzymes of digestive tract and those found in blood are present in inactive form called ______or _______
zymogen or proenzymes.
is a region on the surface of an enzyme to which substrates will bind and catalyzes a chemical reaction.
active site
Enzymes are _________ for the type of the reaction they catalyze and for their substrate.
highly specific
Type of specificity recognized: (4)
- Absolute specificity
- group specificity
- reaction specificity
- stereospecificity
Enzymes with highest specificity and accuracy are involved in __________. These enzymes have proof reading function e.g. _________
copying and expression of genome;
DNA polymerase
Some enzyme require non protein molecule for their activity. So enzymes are conjugated proteins known as ________
holoenzyme
holoenzyme = _______ + _______
apoenzyme + cofactor/coenzyme
Enzyme without non protein part is inactive and called ______
apoenzyme
true or false
cofactors are inorganic compouns.
false
cofactors can be either inorganic or organic compounds.
The polymerization of deoxyribonucleotides into a DNA strand is catalyzed by_________, a holoenzyme. The catalytic activity of this enzyme is catalyzed by the ____________
DNA polymerase
magnesium ion
