2.1 The Nervous System Flashcards
- receive and send information
- communicates and controls throughout the rest of the body
- communicate by means of electrical signals (rapid, specific)
Nervous system
Central Nervous System (2)
Brain
Spinal Cord
Peripheral Nervous System (3)
Cranial nerves
Ganglia outside CNS
Spinal nerves
Cellular Components of the Nervous System
A. Supporting Cells (GLIAL CELLS) - vary in shape & size
- Neuroglia in CNS
- Neuroglia in PNS
B. NEURONS (nerve cells)
Neuroglia in CNS (4)
- Microglia
- Oligodendrocytes
- Astrocytes
- Ependymal cells
- scavenger cells that resemble tissue macrophages and remove debris resulting from injury, infection, and disease
- smaller than astrocytes
- remain stationary until brain tissue becomes injured
- act as microbe scavengers in the brain via phagocytosis
Microglia
- resembles stars
- threadlike branches attach to neurons and to small blood vessels holding both structures together
Astrocytes
Astrocyte branches form a two-later structure called _______ that separates blood tissues and nervous tissue. It protects brain from harmful chemicals that might be found in the blood.
blood brain barrier (BBB)
Neuroglia in PNS (2)
- Schwann cells
- Satellite cells
- neurolemmocytes
- myelinate neurons
Schwann cells
- regulate the chemical environment
Satallite cells
Form the myelin sheath around axon
Oligodendrocytes and Schwann cells
- autoimmune disease possibly triggered by a virus in genetically susceptible individuals
- oligodendrocytes and myelin sheaths of CNS deteriorate and are replaced by hardened scar tissue
- occur especially between 20-40 years of age
- nerve fibers are severed
- myelin sheaths in CNS are gradually destroyed -> short circuits; loss of impulse conduction
- affects mostly young adults
- common symptoms:
> visual problems
> clumsiness
> muscle weakness
> eventual paralysis
Multiple Sclerosis
Normal conduction of action potentials relies on the insulating properties of ______. Thus, defects in this can have major adverse neurological consequences
myelin
- hereditary disorder seen mainly in infants of Eastern European Jewish ancestry
- abnormal accumulation of a certain glycolipid(GM2) in myelin sheath as it accumulates it disrupts conduction of signals
- results in blindness, loss of coordination, dementia- symptoms appear before 1 yr of age, death by 3 or 4
Tay-Sachs Disease