module 13 Flashcards
Senescence
progressive deterioration of physiological function with increasing age
age dependent increase in mortality and decline of fecundity
What does evolution of death do? (Weissmann) (3 pts)
ensures removal of less fit individuals from population to make room for reproductively prolific individuals
long lived individuals have more offspring than short lived which selects against death
acquisition of mutations with age selects for death
Mutation accumulation hypothesis
MA suggests that selection weakly impacts mutations results in late-onset degeneration
- loci can acquire more neutral mutations via drift with age
- only detectable if individuals survive long enough and express symptoms of aging
Antagonistic pleiotropy hypothesis
AP results in strong selection for mutations beneficial early in life but deleterious later in life - aging is a maladaptive byproduct of survival and reproduction during youth
Disposable soma hypothesis
Investment in optimization of somatic cell repair and maintance (for indefinite survival) is not worthwhile since extrinsic mortality will prevent realization - investment in reproduction is more quickly realized.
Transcription/translation in germ line cells evolved towards fidelity and error-checking meiosis.
somatic cells selected for growth
plant senescence
annuals can devote energies towards seed prodctuion - pernnials have a head start on annuals - reduced genetic diversity in perennials subject to rapid environmental/predation changes
self pruning due to low nutrient productivity and accessiblity for pollinators
minimizes abiotic and biotice effects on the plant
major transitions
occurrences in time that set the stage for the evolution of cellular and multicellular forms
Biological ontogeny take homes
- biomolecules could be generated abiotically
- catalytic rnas can transmit information and self-replicate
- cells compartmentalize key biomolecules and increase their encounter frequency
miller-urey exp
showed that mimicking prebiotic conditions in teh lab could result in the production of the 20 most common amino acids
what are the major transitions
molecular replication, information storage and transmission, segregation of 1 and 2, prokaryotes to eukaryotes, unicellular to multicellular, solitary life to multigenerational colonies
transition 3 take homes
Endosymbiosis was fundamental for the emergence of eukaryotes Genetic analyses revealed the bacterial origins of mitochondria and chloroplasts Other forms of endosymbiosis exist Gene and/or metabolite exchange between endosymbiotic partners helps to maintain the relationship
evidence for symbiosis?
separate circular genomes, similar cell size to bacteria, independent replication, genes resemble those form bacteria
Hominoidea
Apes (Hominoidea) are a branch of Old World tailless simians native to Africa and Southeast Asia.
Hominini
or hominins, form a taxonomic tribe of the subfamily Homininae (“hominines”). Hominini includes the genus Homo (humans), but excludes the genus Gorilla (gorillas).
Sahelanthropus
an extinct species of the Homininae (African apes) dated to about 7 million years ago, during the Miocene epoch. The species, and its genus Sahelanthropus, was announced in 2002, based mainly on a partial cranium, nicknamed Toumaï, discovered in northern Chad.
Ardipithecus
is a genus of an extinct hominine that lived during the Late Miocene and Early Pliocene epochs in the Afar Depression, Ethiopia.