Module 11 - Populations Requiring Special Considerations

Question 1

Local reactions will increase with the number of vaccine doses against which 3 diseases?

Answer 1

diphtheria, tetanus and pertussis

Question 2

Arthus reaction is most commonly associated with ??

Answer 2

tetanus toxoid

Question 3

When does GBS (Guillain-Barre Syndrome) usually occur after a vaccine?

Answer 3

0-31 days (although 0-5 days is unlikely - takes longer antigen exposure)

Question 4

When does thrombocytopenia occur?

Answer 4

within 31 days

Question 5

In practise, it is recommended that ____ or _____ vaccine is contraindicated if GBS occurs within 6 weeks of receiving each vaccine respectively.

Answer 5

tetanus or influenza

Question 6

The _______ ______ vaccine is CI in patients with an anaphylactic reaction to eggs.

Answer 6

yellow fever

Question 7

egg-allergic individuals may be vaccinated against influenza using which vaccine without prior influenza vaccine skin test with the full dose, irrespective of a past severe reaction to egg and without any particular consideration including immunization setting

Answer 7

trivalent influenza vaccine (TIV)

Question 8

Have similar recommendations been made for the QIV vaccine and egg-allergic patients?

Answer 8

Yes

Question 9

Can egg-allergic pts get LAIV (live attenuated influenza virus)

Answer 9

no - no data to support this

Question 10

What are examples of immunocompromised individuals?

Answer 10

• asplenia
• congenital immunodeficiencies involving any part of the immune system
• hematopoietic stem cell transplatation
• HIV
• people on corticosteroids and chemotherapy

Question 11

Immunocompromised individuals:

There is NO contraindication to ______ vaccines

Answer 11

inactivated

Question 12

Should immunocompromised people get influenza vaccine yearly?

Answer 12

yes

Question 13

The conjugated pneumococcal 13 talent vaccine is now recommended in individuals with ??

Answer 13

• hematopoietic stem cell transplant
• HIV
• immunosuppressive conditions

Question 14

Meningococcal, pneumococcal and Hib vaccines should be given at least ___ days prior to elective splenectomy or if not possible, ___ or more days post-splenectomy

Answer 14

14, 14

Question 15

For pts with bleeding disorders, when the efficacy is known to be the same for a vaccine, wither it is administered SC or IM, administer the vaccine using the ___ route.

Answer 15

SC

Question 16

immunization with inactivated vaccines is generally stated _____ months post HSCT, except influenza which can be administered ____ months post HSCT

Answer 16

12, 6

Question 17

do not administer live vaccines until ___ months post HSCT

Answer 17

24

Question 18

Patients undergoing HSCT are at particularly high risk of ???

Answer 18

Hib and pneumococcal disease

Question 19

For patients undergoing solid organ transplant, it is best to immunize ______ transplantation

Answer 19

before

Question 20

In general, vaccination should not be re-initiated until at least _____ months after transplantation

Answer 20

6-12

Question 21

What inactivated viral and bacterial vaccines or toxoids can be safely given to pregnant women?

Answer 21

• hep A and B
• influenza
• meningococcal and pneumococcal

Question 22

T or F: If a live vaccine is inadvertently given to a pregnant woman, termination of the pregnancy is recommended.

Answer 22

False - not recommended

Question 23

What type of vaccines are CI in pregnant patients?

Answer 23

live attenuated virus vaccines

Question 24

Is breastfeeding a CI for any type of vaccines?

Answer 24

No

Question 25

When should travellers see their clinicians in order to get the required vaccines?

Answer 25

2-3 months before they go