Module 1 - The Immune System & Vaccines Flashcards
______ immunity is nonspecific
Innate
Innate immunity has no ____
memory
Innate immunity: fast or slow?
fast
Innate immunity: does it improve with repeated exposure to a given infection
No
What is passive immunity?
immediate protection provided through the transfer of antibodies from immune individuals (ex. through placenta from mom to baby)
With passive immunity, protection is __________
temporary
What are the two branches of adaptive immunity?
- humoral immunity
- cell-mediated immunity
When _-cells are differentiating, a portion of these become memory cells
B
When memory cells are re-exposed to the specific antigen, they rapidly convert to what kind of cells?
antibody-secreting plasma cells
primary role of vaccines is to induce ______ immunity and to provide immunological memory
active (adaptive)
_________ polysaccharide antigens have limited immune response and no immune memory
Unconjugated
A minimal interval of ___ weeks between primary dose allows development of successive waves of antigen specific primary response without interference
4
What happens if you need to do rapid scheduling and inject vaccines before the 4 week interval?
this schedule will induce less persistent responses than when the same number of vaccines doses are given at longer (1-2 months) intervals
Extremes of age of life generally have _____ antibody persistence
shorter
T or F: innate immune system stimulates the adaptive immune response
True
The adaptive immune system is an _____ specific defence mechanism
antigen
Effector ___ cells are helper cells that facilitate the humoral immune response
T4
Effector T8 are _____ cells that help to destroy infected cells
cytotoxic
The humoral system is responsible for _____ production
antibody
