Module 1: Biochem & The Cell Flashcards
Biochemistry
study of living organisms by understanding how organisms arise from complex interactions of different biomolecules
Human body composed of…
mainly H atoms (>60%), followed by C & O
Oxygen
building block of biomolecules and water
Carbon
building block of all organic molecules
Hydrogen
components of water, biomolecules, main component of pH in body fluids
Nitrogen
component of pr- and nucleic acids
Phosphorus
component of nucleic acids
Sulfur
component of pr-
Element
basic substance that cannot be broken down into anything more basic
Macromolecule
polymer of monomeric building blocks
polymerization like condensation rxn-removal of water
Nucleic acids (DNA & RNA)
monomer: nucleotides
contains: ribose sugar (DNA has H; RNA has OH at 2’ C), phosphate group at 5’, 1’ C binds one of 4 nitrogen bases (A, G, C, T; RNA uses U instead of T)
DNA= double strand
RNA=single strand
Contains all elements except S
Proteins
Amino acid structure
made of 20 diff kinds of aa
Amino acids contain: amino group, carboxyl group, specific R group
to form a pr-, amino group from one aa creates a covalent peptide bond with carboxyl of another aa
Contain all elements except P
Carbohydrates
Glucose & Sucrose/lactose
Glucose: monosaccharide -only 1 sugar ring
Sucrose/lactose: disaccharide -held by covalent bonds
Contain: C, H, O
Lipid Bilayer
barrier which keeps inside in and outside out
Selective/Semi-permeable: allows cell to maintain diff enviro on either side
Amphipathic
The lipid bilayer is such
one end of molecule hydrophilic (water loving -head), the other end is hydrophobic (tail)
Eukaryotic Cells
compartmentalizing/segregating process, cell-to-cell communication, energy conservation
DNA function
genetic code passed on from gen to gen
blueprint for making pr-
Protein function
enzymes, maintaining cell structure, cell division
Carbohydrate function
broken down to make energy, structural component
Cell envelope (pro cells)
contains cell membrane and peptidoglycan layer (combo of aa and sugars that give cell its shape/rigidity, protects cell from enviro, structural support)
Gram negative bacteria
bacteria has 2 membranes
Gram positive bacteria
bacteria has 1 membrane
Gram staining
stains peptidoglycan layer Gram positive bacteria: stain deep purple (thick peptidoglycan layer) Gram negative bacteria: stain pink/red (thin peptidoglycan layer)
Pili
allow bacteria to attach to surfaces/other cells
Flagella
allow bacteria to swim through aq enviro
Nucleic (pro cells)
store DNA and associated pr-
Cytoplasm vs cytosol
hydrophilic solution that fills cell and enclosed by plasma membrane
contains cytoplasm and other structures suspended in it
Plant Cell
Monomers–>polymers–>supramolcules complexes
size increases up hierarchy chain
lot easier to make/break bonds in larger complexes b/c non-covalent interactions much weaker
Animal cell
contain single membrane (lipid bilayer) around entire cell
inside much more compartmentalized into section which enclosed by lipids
Endomembrane System
grouping of membrane and organelles that function together to modify/package/transport molecules