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Phase 1 powerpoint Cardio > Modifying heart function > Flashcards

Modifying heart function Flashcards

1
Q

What does increasing cardiac tension lead to?

A

Increase Ca2+ sensitivity of troponin C
Increase Ca2+ release from the SR

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2
Q

Define Frank Starling’s law?

A

The longer the fibre length, the stronger the contraction
This is an ionotropic effect

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3
Q

Complete equation:
CO=
BP=
Pulse pressure=
Mean arterial pressure=
Stroke volume=
Poiseuille’s equation Flow=
Ohms law Flow=

A
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4
Q

Write equation for heart rate?

A

Heart rate= CO/SV

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5
Q

Write an equation for total peripheral resistance?

A

TPR=BP/CO

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6
Q

Write an equation for resistance?

A

pressure/flow

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7
Q

Define preload?

A

Ventricular stretch at end diastole

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8
Q

Define afterload?

A

Pressure that the chambers need to generate to eject blood out of heart

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9
Q

What affects pre-load?

A

Venous blood pressure
Rate venous return

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10
Q

What affects afterload?

A

Vascular resistance
Pulmonary vascular resistance

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11
Q

When does pre/after load occur?

A

Preload- Diastole
Afterload- Systole

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12
Q

Is preload volume or pressure?

A

Volume

Afterload- pressure

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13
Q

What is preload dependent on?

A

Amount ventricular filling

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14
Q

What is afterload dependent on?

A

Arterial blood pressure
Vascular tone

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15
Q

Define systole? Range?

A

Maximum arterial pressure during contraction of left ventricle
Max BP inside arteries
Occurs left ventricle contracted
90-120

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16
Q

Define diastole? Range?

A

Minimum arterial pressure during relaxation of left ventricle
Min BP inside arteries
Occurs left ventricle relaxed
60-80

17
Q

Does diastole or systole undergo fluctuations?

A

Diastole

18
Q

What increases with age diastole or systole?

A

Diastole

Systole decreases with age

19
Q

What factors affect heart rate?

A

Hormones
Age
Fitness lvls
Autonomic innervation
Smoke

20
Q

What factors affect stroke volume?

A

Heart size
Fitness lvls
Gender
Contractility
Duration contraction
Preload
Afterload (resistance)

21
Q

How calculate stroke volume?

A

SV= EDV-ESV

Phase 1 powerpoint Cardio (19 decks)

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