Mod 7 (ch7) Flashcards

1
Q

major functions of the muscular system

A
  1. movement of the body
  2. maintenance of posture
  3. respiration
  4. production of body heat
  5. communication
  6. constriction of organs and vessels
  7. contraction of the heart
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2
Q

skeletal muscle (factors)

A

Location - attached to bones
Cell shape - long, cylindrical
Nucleus - multiple, peripherally located
Striations - yes
Control - voluntary and involuntary (reflexes)
Function - body movement

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3
Q

Smooth muscle (factors)

A

Location - walls of hollow organs, blood vessels, and glands
Cell shape - spindle-shaped
Nucleus - single, centrally located
Special cell to cell attachments - gap junctions join some smooth muscle cells together
Autorhytmic - yes (some smooth muscle)
Control - involuntary
Function - moving food through digestive tract, emptying the urinary bladder, regulating the blood vessel diameter. contracting many gland ducts

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4
Q

cardiac muscle (factors)

A

Location - heart
Cell shape - branched, cylindrical
Nucleus - single, centrally located
Special cell to cell attachments - intercalated disks
Striations - yes
auto rhythmic - yes
Control - involuntary
Function - pumping blood; contractions provide the major force for propelling blood through blood vessels

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5
Q

4 major function characteristics of muscle tissues

A
  1. contractility
    - the ability of muscle to shorten forcefully, or contract
  2. excitability
    - the capacity of muscle to respond to a stimulus
  3. extensibility
    - means that a muscle can be stretched beyond its normal resting length and still be able to contract
  4. elasticity
    - is the ability of muscle to recoil to its original resting length after it has been stretched
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6
Q

skeletal muscle - contractility

A

skeletal muscle contraction causes the structures to which they are attached (such as a bone) to move

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7
Q

smooth muscle - contractility

A

smooth muscle contraction increases pressure inside hollow organs, such as the intestines

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8
Q

cardiac muscle - contractility

A

cardiac muscle contraction increases pressure inside the heart

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9
Q

skeletal muscle - excitability

A

the stimulus to contract is from nerves that we consciously control

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10
Q

smooth and cardiac muscle - excitability

A

smooth and cardiac fibres contract spontaneously but also receive involuntary neural signals and hormonal signals to modulate force or rate of contraction

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11
Q

skeletal muscle

A

when associated w connective tissue, constitutes approx 40% of body weight
- also called striated muscle
- consists of: skeletal muscle tissue, nervous tissue, connective tissue, and adipose tissue
- each muscle cell is called a muscle fibre

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12
Q

what are the 3 layers of connective tissues in skeletal muscles?

A
  1. epimysium
  2. perimysium
  3. endomysium
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13
Q

epimysium

A

forms a connective tissue sheath that surrounds each skeletal muscle
- separate the muscles from nearby structures

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14
Q

perimysium

A

subdivides each whole muscle into numerous, visible bundles of muscle fibres (cells) called fascicles
- loose connective tissue serving as passageways for blood vessels and nerves that supply each fascicle

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15
Q

endomysium

A

is a delicate layer of connective tissue that separates the individual muscle fibres within each fascicle
- serves as passageway for nerve fibres and blood vessels that supply each separate muscle fibre

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16
Q

tendons

A

the protein fibres of the 3 layers of connective tissues blend into one another and merge at the ends of most muscles to form tendons, which attach muscle to bone

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17
Q

striated

A

alternating light and dark bands give the muscle fibre a striated, or striped appearance

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18
Q

2 main aspects to muscle contraction

A
  1. electrical component
  2. mechanical component
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19
Q

electrical component - 3 muscle fiber components that respond to and transmit electrical signals

A
  1. sarcolemma
    - cell membrane of muscle fibres
  2. transverse tubules
    - tubelike inward folds of the sarcolemma
    - carry electrical impulses into the centre of the muscle fibre so that the muscle fibre contract as a whole
  3. sarcoplasmic reticulum
    - highly specialized smooth endoplasmic reticulum in skeletal muscle fibres that stores high levels of Ca2+
20
Q

mechanical component structure - contractility is due to 2 main structures in muscle fibers

A
  1. myofibrils
    - bundles of protein filaments
    - its the protein filaments in the myofibrils that interact to shorten the muscle fibre during contraction
  2. myofilaments
    Two types of myofilaments:
  3. actin myofilaments or thin filaments
  4. myosin
    - both arranged in ordered units called sarcomeres this is the structural and functional units of skeletal muscles
21
Q

sarcomeres

A

Smallest portion of a muscle that can contract
- Z disks are the anchor for actin myofilaments
3 regions:
1. two lighter-straining regions called I bands
2. central darker-staining region, called an A band
- each A band contains actin and myosin myofilaments overlapping, except in the centre b/c that is called the H zone which only contains myosin myofilaments (thick filaments)
- the middle of the H zone has a dark line called the M line, which consists of delicate protein filaments that hold the myosin filaments in place

22
Q

actin myofilaments is composed of which 3 proteins?

A
  1. actin
  2. tropomyosin
    - in a relaxed muscle, this is covering the attachment sites on the actin
    - a muscle cannot contract until the tropomyosin moves to uncover the active sites
  3. troponin
    - consists of 3 subunits: 1: anchors the troponin to the actin, 2: subunit that prevents the tropomyosin from uncovering the actin attachment sites in a relaxed muscle, 3: subunit that binds Ca2+
23
Q

myosin myofilaments

A

composed of elongated myosin molecules which consist of a rod portion and 2 myosin heads

myosin heads 3 properties:
1. heads bind to active sites on the actin molecules to form cross-bridges to contract the muscle
2. the heads are attached to the rod portion that bends and straightens during contraction
3. heads break down ATP for contraction

24
Q

muscle fibre and motor neurons

A

each muscle fibre is in contact w a branch of a motor neuron axon from the brain or spinal cord, these motor neurons carry electrical signals (action potentials) which cause action potentials in the muscle fibre and then muscle contraction happens

25
neuromuscular junction/synapse
the point of contact of motor neuron axon branches w the muscle fibre is the neuromuscular junction or synapse - rests on a portion of the sarcolemma - muscle cell membrane in the area of the junction is called the motor endplate or postsynaptic membrane Consists of: 1. axon terminals - called presynaptic terminal - area between presynaptic terminal and the muscle fibre is the synaptic cleft - contains synaptic vesicles which contain neurotransmitters 2. area of the muscle fibre sarcolemma they innervate
26
sliding filament model
mechanism by which actin and myosin myofilaments slide over one another during muscle contraction - when relaxed they aren't over one another - when contracted they ARE over one another
27
what is the process of the neuromuscular junction
1. AP enters presynaptic terminal and opens Ca+ channels 2. this stimulates exocytosis of vesicles 3. neurotransmitter (Ach) is released in to the synaptic cleft 4. neurotransmitter binds to receptors on the sarcolemma membrane 5. binding causes NA+ channel to open 6. rush of sodium into cell causes AP signal 7. breakdown of ACH - enzyme
28
what occurs because of the AP to the sarcolemma membrane?
the AP moves down the membrane changing the resting potential and opening ion channels
29
what does the T tubule do
brings the AP down deeper into the muscle cell so AP can cause contraction
30
what does calcium do in contraction because of the ap
the tropomyosin protein strands that block the actin bonding sites are moved when calcium bonds to the troponin proteins myosin heads bond and form cross bridges
31
ap change of membrane potential in muscles
1. sarcolemma membrane resting membrane is -85, NA is outside K+ is inside, 2. channels are the same as neurons, + Na+/k+ (3 sodium out, 1 potassium in) 3. ap opens sodium channels which stimulates depolarization 4. repolarization occurs and NA channels close and K+ channels open letting potassium out and the gated Na+/K+ pump
32
what maintains the negative electric potential inside the cell
proteins that are negative
33
how is ATP utilized in the cycle of the cross bridges of myosin?
1. ap cause calcium release (adp attached) 2. myosin can bond creating cross bridge (adp + free phosphate released) 3. power stroke - movement relative to actin (adp released) 4. atp binds to myosin head and allows it to release from actin 5. adp and p is created by breaking down ATP 6. recovery stroke, myosin moves back to the right and becomes read to attach again
34
how are adp and p present before contraction
they are attached to the heads already from the past hydrolysis of atp from the last contraction or movement
35
how do we regulate muscle force
by regulating the amount of force a muscle produces by controlling how many muscle cells are stimulated
36
what is a motor unit
a single motor neuron and the muscle fibre it innervates
37
are muscle fibres the same in a motor unit?
yes they are all the same fiber type in each unit
38
what is motor unit recruitment?
when the action potential recruits a motor unit
39
what are the three specialized muscle fibre types
SO Slow twitch oxidative (type 1) FOG Fast twitch oxidative Glycoltic FOG type 2 a FG Fast twitch Glycolytic (FG type 2b)
40
what is slow twitch oxidative fibres
have a high capacity for aerobic metabolism (using oxygen) endurance activities
41
what are fast twitch oxidative (TYpe IIa)
intermediate characteristics for aerobic and anaerobic metabolism endurance activities in endurance trained muscles
42
what are fast twitch glycolytic (FG) (Type IIb)
high capacity for anaerobic (without oxygen) force and power output
43
aerobic based exercise
endurance training
44
energy source for anaerobic excersise
partial release of energy from glucose – fast but limited quantity - use bonds of glucose molecule
45
immediate use energy source
adenylate kinase and creatine kinase very fast but very limited quantity weight lifting
46
aerobic pathway energy source
complete energy release from glucose and fats - slow but very large quantity