Mod 7 - Cardiac Meds Flashcards
what does vasoconstriction do to the blood pressure?
increase BP
what does vasodilation do to the blood pressure?
decrease BP
What is the most important implementation when giving meds?
Determine is it safe to give this medication to this patient at this time
What are we worried about when giving meds that get rid of fluid?
BP dropping
what meds get rid of fluid
diuretics (furosemide), ACE inhibitors (lisinopril), ARBs (losartan)
When are we worried about BP
if the medication is changing vessel size or fluid levels
When would you hold a med?
antihypertensives BP <100/60
HR <60
warfarin - if PT is too high or low range depends normal 0.8-1.2, on warfarin 2.0-3.0, with mechanical valve 2.5-3.5
heparin in PTT is too high or low
Why could someone have a low HR
just woke up, other meds, athlete, normal
what happens during vasodilation of veins
venous return slows so decreases the work of the heart
what happens during vasodilation of arteries (ateriodilation)
decrease in BP
What is the first line of defence for HTN
Furosemide (Diuretics)
Brief description of the RAAS System
low BP and low volume causes release of renin from kidneys. that stimulates conversion of angio 1 to angio 2 in the lungs with angioconverting enzyme. angio 2 causes vasoconstriction increases BP, and the release of aldosterone which retains Na+ and water and excretes K+ which increases blood volume (neg feedback loop).
Where do ACE inhibitors interrupt the RAAS system
blocks the converting enzyme for angio 1 to angio 2
where do ARBs interrupt the RAAS system?
ARBs block angio 2 receptors and do not allow them to do their job
what is the normal range for PT?
0.8-1.2 secs
what is the therapeutic range for someone on warfarin
2.0-3.0 secs
what is the therapeutic range if the pt has a mechanical valve
2.5-3.5 seconds
What classifications of medications do you check just BP for?
Diuretics (Furosemide), ACE Inhibitors (Lisinopril), ARBs (Losartan), Nitrates (Nitroglycerin),
What classifications of medications do you check just HR for?
Cardiac Glycosides (digoxin)
What classifications of medications do you check BP and HR for?
Calcium Channel Blockers (diltiazem), Beta Blockers (metoprolol)
Which will affect aPPT hep subq or hep IV
Hep IV
what can subq hep lead to?
Heparin‐induced thrombocytopenia (HIT). a potentially devastating immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin.
what is the antidote for Heparin
Protamine sulfate
What is the antidote for Warfarin
Vitamin K
What medications does grapefruit juice interact with?
Calcium channel blockers, warfarin, some statins
how does digoxin work?
It inhibits the Na+/K+ pump resulting in an increase of intracellular Na+ and an influx of Ca2+ into cardiac cells. causes the cardiac muscle fibres to contract more efficiently and increase CO (slower, stronger beat)
what is the O/E of digoxin
bradycardia, fatigue, digoxin toxicity (nausea, vomiting, halos)