MOD: 3 LESSON 6: What is non-Hodgkins lymphoma?

Question 1

The majority of non-Hodgkin’s lymphomas involve:
A. B lymphocytes.
B. T lymphocytes.
C. macrophages.

Answer 1

A. B lymphocytes.

Question 2

True / False - Non-Hodgkin’s lymphomas often spread throughout the body rather than remaining isolated in swollen lymph nodes.

Answer 2

TRUE

Question 3

True / False - Non-Hodgkin’s lymphomas include a collection of tumors that differ greatly with respect to behavior, cell composition, and response to treatment.

Answer 3

TRUE

Question 4

The Rappaport system classifies non-Hodgkin’s lymphomas according to what four criteria?

Answer 4

grade;
growth pattern;
cell type;
degree of differentiation

Question 5

Match the following:
\_\_\_\_ the most common type in children
\_\_\_\_ often exhibit only minor symptoms
\_\_\_\_ may be rapidly fatal if not treated
\_\_\_\_ chemotherapy often used for palliation rather than cure

A. low-grade lymphomas
B. intermediateor high-grade lymphomas

Answer 5

Match the following:
B. intermediateor high-grade lymphomas____ the most common type in children

A. low-grade lymphomas____ often exhibit only minor symptoms

B. intermediateor high-grade lymphomas____ may be rapidly fatal if not treated

A. low-grade lymphomas____ chemotherapy often used for palliation rather than cure

Question 6

Stage I low-grade lymphomas are generally treated with:

Answer 6

localized radiation therapy

Question 7

List a preferred chemotherapeutic regimen for the treatment of low-grade (indolent) non-Hodgkin’s lymphomas.

Answer 7

any one:
CVP (cyclophosphamide + vincristine + prednisone);
chlorambucil ± prednisone;
cyclophosphamide

Question 8

Which of the following is not a preferred combination regimen used for the treatment of intermediate- or high-grade non- Hodgkin’s lymphomas?

A. CHOP: cyclophosphamide + hydroxydaunorubicin (doxorubicin) + ONCOVIN® (vincristine) + prednisone

B. COP-BLAM: bleomycin + ADRIAMYCIN® (doxorubicin) + cyclophosphamide + ONCOVIN® (vincristine) + prednisone + procarbazine

C. ABVD: ADRIAMYCIN® (doxorubicin) + bleomycin + vinblastine + dacarbazine

D. BACOP: bleomycin + ADRIAMYCIN® (doxorubicin) + cyclophosphamide + ONCOVIN® (vincristine) + prednisone

Answer 8

Which of the following is not a preferred combination regimen used for the treatment of intermediate- or high-grade non- Hodgkin’s lymphomas?

C. ABVD: ADRIAMYCIN® (doxorubicin) + bleomycin + vinblastine + dacarbazine