MNSR 36 - Human Reproduction: embryological origins; Male System Flashcards

1
Q

reproduction

A

for species to survive they must multiply and produce new individuals to replace those lost to predators, parasites and old age
implies transfer of genetic material from one partner to another

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2
Q

hermaphroditism

A

possessing both male and female sex organs in the same individual

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3
Q

examples of organism that feature aphroditism

A

lower invertebrates e.g. Platyhelminthes (i.e. flat worms),

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4
Q

parthenogenesis

A

reproduction from a female gamete without fertilisation by a male gamete
unfertilized egg develops to maturity via asexual reproduction

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5
Q

terrestrial tetrapods

A

repitles, birds and mammals - developed a mechanism of internal fertilization as they live in a terrestrial environment

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6
Q

oviparous

A

laying eggs

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7
Q

vviparous

A

producing live young

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8
Q

gonads

A

reproductive organs e.g. testis and ovaries

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9
Q

where do both the testis and ovary develop from

A

mesodermal genital ridge of the embryo

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10
Q

where is mesodermal genital ridge

A

medial to the mesonephros - nearby developing intermediate kidney

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11
Q

____ or ___are gradually taken over for reproductive purposes in males

A
  1. mesonephric

2. wolffian ducts

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12
Q

1.___ or2. ___ are taken over for reproduction in

females

A

1.paramesonephric or Mullerian

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13
Q

in males how are sperm conducted to the outside

A

in all male vertebrates, sperm are conducted to the outside via the closed tubes of the excretory system

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14
Q

in females how do ova shed coelom

A

ova are shed into the coelom and then pass into a special tube, the fallopian tube or Müllerian duct

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15
Q

where are the testes

A

upper lumbar region of coelomic cavity

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16
Q

how does the position of scrotal sacs change through fetal development

A

However, in most mammals the testes descend into scrotal sacs during foetal development passing through the inguinal canal

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17
Q

what also descends with the testes in fetal development

A

with the testes descends the sperm duct,

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18
Q

gubernaculum

A

testes and sperm duct with their nerve and blood supply and a fold of mesentery called the gubernaculum

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19
Q

how many seminiferous tubules are in each testis

A

1,000 highly coiled seminiferous tubules

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20
Q

function of seminiferous tubules

A

are open at both ends and produce spermatozoa into the rete testis which acts as a reservoir

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21
Q

vasa efferentia

A

A series of fine ciliated tubes the vasa efferentia (or efferent ducts), that connect the rete testis with the epididymis

22
Q

epididymus

A

a single long convoluted duct lined with pseudostratified columnar epithelium with stereocilia (microvilli);

23
Q

how are immobilised spermatoza transported

A

transported through the epididymis by peristalsis of the layer of smooth muscle in the wall

24
Q

function of epididymus

A

Functionally the epididymis is the site of sperm maturation (acquire motility and ability to fertilize)

25
Q

how does the spermatoza transported prior to ejaculation

A

epididymis (by peristalsis of the smooth muscle)
the vas deferens
bladder
prostate gland
urethra
in males the urethra is a common urino-genital duct.

26
Q

vas deferens

A

a muscular tube, which brings them back into the abdominal cavity;

27
Q

2 cavernous bodies in penis

A

corpora cavernosa - outer
corpus spongiosum - inner
surround the urethra

28
Q

how are blood supplied from arteries

A

Essentially helicine arteries supplying the cavernous bodies dilate filling the cavernosa with blood while at the same time the veins are compressed

29
Q

pH of semen

A

7.5

30
Q

average volume of semen per ejaculation

A

3.5ml

31
Q

normal amount of spermatoza per ml

A

120 million spermatazoa/ml

32
Q

sperm count of infertile men

A

less than 20 million spermatozoa

33
Q

accessory sex glands of male reproductive system

A

seminal vesicles
prostate gland
cowpers glands

34
Q

function of seminal vesical

A

produce viscous fluid into vas deferens
makes up to 60% of semen volume
provides fructose for ATP production and enables sperm to swim

35
Q

function of prostate gland

A

produces a thin milky alkaline fluid containing citric acid (used for ATP production by sperm)
acid phosphatase neutralise acidity of vagina which has pH of 3.5

36
Q

function of cowpers gland/bulbourethral

A

(bulbo-urethral) produces a viscous mucous secretion for lubrication

37
Q

path of secretions from accessory glands

A

Cowper’s secretions -> prostatic fluid –> spermatozoa –>seminal vesicle secretions

38
Q

how does consistency change and what enzyme contributes to this change

A

the semen initially coagulates into a gelatinous mass and then dissolves over the next 15 to 20 minutes;
this is helped by a prostatic proenzyme

39
Q

histology of testis - seminiferous tubules

A

germinal epithelium - undergoes meiosis those cells sit on a
basement membrane
- outside that membrane have fibroelastic connectice tissue and myoid cells that are muscle like cells can contract

40
Q

describe cells resting on basement membrane

A

type A1 spermatogonia - divide by mitosis to make type B spermatogonia
diploid cells

41
Q

Type B spermatagonia divide to make..

A

these type B spermatogonia now undergo a series of mitotic divisions to produce primary spermatocytes (2N);

42
Q

primary spermatocytes (2N); divide

A

and these divide by meiosis (‘SPERMATOGENESIS’) to produce two secondary Spermatocytes (N);

43
Q

why are secondary spermatocytes rarely seen

A

they rapidly undergo the second meiotic division to produce the haploid spermatids (N).
these by a process of SPERMIOGENESIS differentiate into spermatozoa, which are stored in the epididymis;

44
Q

what hormone controls process of spermatogenesis

A

FSH from pituitary gland

45
Q

leydig cells

A

between the seminiferous tubules are the Leydig cells, which secrete testosterone

46
Q

testicular descent

A

the descent of the testis but the scrotal sac is high up or inguinal canal or abdomen
This is especially serious where the spermatic cord is not long enough to travel the complete journey
can lead to malignancy if elft intreated

47
Q

testicular malignancy

A

Malignancy may quickly spread to Inguinal nodes

Males should examine themselves regularly as do women their breasts

48
Q

inguinal hernia

A

The internal structures (intestines or fat) are forced out through the weakness in the abdominal wall (inguinal canal)

49
Q

what gender is inguinal hernia more common and why

A

This is more common in males as the canal is larger

50
Q

main cause of erectile dysfunction

A

insufficient release of nitric oxide which relaxes the smooth muscle of the penile arterioles and erectile tissue.