Mnemonics/Lists General Flashcards
List of Eschar Conditions
DEEP RAYS
Diphtheria (cutaneous) can simulate ecthyma or impetigo, Disseminated Fungal Infection Ecthyma Ecthyma gangrenosum Pressure ulcer/trauma Rickettsia, rickettsial pox Anthrax/Tularaemia Yersinia infection (10% have primary cutaneous lesion from flea bite carrying yersinia pestis) - necrotic lesions can develop Scrub typhus (Orientia tsutsugamushi)
X-Linked Recessive Conditions
CHADS Kinky WIFE CHANdra Chronic Granulomatous Disease Hunter Disease Anhidrotic Ectodermal Dysplasia Dyskeratosis Congenita SCID Kinky Hair Disease Wiskott Aldrich Syndrome Ichthyosis (X-linked) Fabry Disease EDS (not type V - 'other', and IX - not EDS anymore as not collagen defect) Chondrodysplasia Punctata (not Conradi-Hunermann type) Hypohidrotic ED with immunodeficiency Agammaglobulinaemia, Bruton N Lesch (N)yan Syndrome
X-Linked Dominant
BIG ChOMP Bazex Syndrome (not acrokeratosis paraneoplastica) Incontinentia Pigmenti Goltz Syndrome (Focal Dermal Hypoplasia) CHILD Syndrome Orofacial Digital Syndrome MIDAS (micrognathia, dermal aplasia, sclerocornea) Chondrodysplasia punctata
Deep lesion (no epidermis/upper dermis seen)
Rheumatoid nodule, malignant fibrous histiocytoma, neurothekeoma, paraffinoma, giant cell tumor of tendon sheath, nodular fasciitis, myxoid liposarcoma, angiolipoma, angioleiomyoma, +/- neurilemmoma, gout, hibernoma
<p>Painful tumors: </p>
<p>BLEND AN EGG Blue rubber bleb, leiomyoma, eccrine spiradenoma, neurilemmoma, dermatofibroma, angiolipoma, neuroma, endometrioma, erythema nodosum glomus tumor, glomangioma, granular cell tumour
Was published in JAAD 1993</p>
Polypoid
Accessory tragus, digital fibrokeratoma
Acral
Digital fibrokeratoma, verruca, supernumerary digit, amputation neuroma, myxoid cyst
Conditions that can show minimal histological change
Tinea versicolor, macular amyloidosis, ichthyosis vulgaris, telangiectia macularis eruptiva perstans, vitiligo, urticaria
Squared off (‘boxcar’) biopsy
Scleredema
pretibial myxedema
morphea
advanced NLD
<p>Spindle Cell Tumours</p>
<p>SLAMDUNK
SCC Spindle Cell (CK 903 and HMW-keratin),
Leiomyomsarcoma (Desmin and SMA),
Angiosarcoma (CD31 and CD34),
Melanoma - Spindle Cell (S100 and MART1 +/-),
DFSP (CD34 POS, Neg FXIIIa and stromelysin, unlike DF),
Undifferentiated Pleomorphic Sarcoma/MFH and AFX (CD68, CD10, Procollagen I),
Nodular fasciitis (HSP47, Actin, NEGATIVE keratin, desmin, S100, CD34),
Kaposi's Sarcoma (CD31, CD34, HHV-8)</p>
Differential for small blue cells (histologically)
MCC
Lymphoma
Carcinoma
Melanoma
RASopathies
Capillary malformation-AV malformation syndrome
Autoimmune lymphoproliferative syndrome
Cardiofaciocutaneous syndrome
Hereditary gingival fibromatosis type 1
Neurofibromatosis type 1
Noonan syndrome
Costello syndrome, Noonan-like[1]
Legius syndrome, Noonan-like
Noonan syndrome with multiple lentigines, formerly called LEOPARD syndrome, Noonan-like
Kawasaki Disease Criteria Mnemonic
RCH website too
CRASH + Burn
Burn
- Fever for 5+ days + 4/5 of:
Conjunctivitis (mostly nonexudative bilat injection)
Rash (polymorphous, EMlike, scarlatiniform, macular)
Adenopathy (one node >1.5cm)
Strawberry tongue + Lip Erythema/fissuring
Hand/Feet swelling +/- desquamation in convalescence
**can have fewer than 4/5 if if coronary artery abnormalities are present.
Common findings outside the diagnostic criteria include irritibility arthritis, aseptic meningitis, sterile pyuria and dysuria.
KD is the second most common vasculitis in childhood after Henoch Schonlein purpura, and is the most commoncause of acquired heart disease in children in developed countries causing coronary artery aneurysms (CAA).
Fast growing mycobacterium
Fast As a Cheetah FAC
M. Fortuitum
M. Abscesses
M. Chelonae
NF1 Criteria Mnemonic
2+ of CAFE SPOt:
C: café-au-lait spots (6+ CALM or 2+ NF or 1 plexiform NF (CALM >0.5cm prepubertal, >1.5cm postpubertal))
A: axillary or inguinal freckling (crowe’s sign axillary)
F: fibromas (neurofibroma (two or more) or plexiform neurofibroma (one))
E: eye hamartomas (Lisch nodules)
S: skeletal abnormalities, e.g. sphenoid wing dysplasia, leg bowing/long bone cortex thinning
P: positive family history
Ot: optic tumour (optic nerve glioma)
Oral Ulcers - Mnemonic
ILL MOUTH IS Bad Infection LP Lupus Malignancy (SCC, Haem) Other (Contact) UC, Crohns, Coeliac Trauma Haemantic (Iron, B12, Folate) Immunobullous SJS, TEN, EM, Sweets Behcet Disease
SLE Dx Criteria Mnemonic
ACR and SLICC
1993 ACR Criteria
Either serially or simultaneously, during any interval of observations, 4+ of:
MD SOAP BRAIN
Malar Rash
Discoid Rash
Synovitis (pleuritis, pericarditis)
Oral Ulcers
Arthritis
Photosensitivity
Blood - haemolytic anaemia, leukopaenia, lymphopaenia, thrombocytopaenia
Renal - usually nephrotic >0.5g/day proteinuria or casts
ANA + (95%)
Immunogical: Anti Sm Abs, Anti-dsDNA, APLA Abs (cardiolipin or LAC or known false pos syph serology)
Neurological (Psychosis/Seizures)
2012 SLICC Criteria
At least 4 of 17 criteria, including at least 1 of the 11 clinical criteria and one of the six immunologic criteria, or that the patient has biopsy-proven nephritis compatible with SLE in the presence of antinuclear antibodies (ANA) or anti-double-stranded DNA (dsDNA) antibodies. For the SLICC criteria, criteria are cumulative and need not be presently concurrently.:
A CHRONIC RASH
A-cute Rash (Malar, SCLE, Bullous, TEN-Lupus, Photosens rash)
C-hronic Rash (discoid/tumid/pannic)
H-air Loss (diffuse thinning or frag with broken hairs, other causes excluded)
R-enal Abn (>0.5g/day or casts)
O-ral/nasal ulcers (excl other causes)
N-eurological (Sz, Psychosis, mononeuritis multiplex, neuritis/neuropathy, acute confusional state)
I-mmune C-riteria (1 point each - ANA, dsDNA, Sm, APLA, Complement C3orC4orCH50, Direct Coombs Pos if Hb normal)
R-educed WCC (1 point leuk OR lymph, 1 point platelets)
A-rthritis
S-ynovitis
H-aemolytic Anaemia
Slow Growing Mycobacteria Mnemonic
BUM TASKS
Mycobacterium…
Bovis Ulcerans Marinum Tuberculae Avium Scrofulaceum Kansasii Szulgai
Sporotrichoid Spread Differential Mnemonic
globaldermie
CAT N SPLAT (not comprehensive supposedly)
Cat scratch disease (bartonella henselae) Atypical mycobacteria (esp marinum) Tuberculosis Nocardia Sporotrichosis Phaeohyphomycosis Leishmaniasis Anthrax Tularemia
Criteria for Hypocomplementaemic Urticarial Vasculitis Syndrome HUVS
(Almost always in women) o Urticaria for 6/12 (maj - needed) o Hypocomplementaemia (maj - needed) o Minor (2 of): - Vasculitis on bx, - arthralgia, - eyes (uveitis/episcleritis), - glomerulonephritis, - recurrent abdo pain, - pos C1q precipitant test
DDx Collodion Baby
Bol
In order of Occurence:
Self-improving collodion ichthyosis - Always
Lamellar ichthyosis - Common
Congenital ichthyosiform erythroderma - Common
Trichothiodystrophy - Fairly common
Autosomal dominant lamellar ichthyosis - Rare
Autosomal dominant congenital ichthyosiform erythroderma - Rare
Sjögren–Larsson syndrome -Rare
Infantile Gaucher disease -Rare
Ichthyosis, intellectual disability, and spastic quadriplegia - Rare
Ectodermal dysplasias (EDs) - Very rare
Neutral lipid storage disease - Very rare
Conradi–Hünermann–Happle syndrome - Very rare
CELTIC SINS
C-ongenital ichthyosiform erythroderma - Common (+AD CIE Rare)
E-ctodermal dysplasias (EDs)* - Very rare
L-amellar ichthyosis - Common (+AD LI Rare)
T-richothiodystrophy - Fairly common
I-nfantile Gaucher Disease - Rare
C-onradi–Hünermann–Happle syndrome - Very rare
S-elf-improving collodion ichthyosis - Always
I-chthyosis, intellectual disability, and spastic quadriplegia - Rare
N-eutral lipid storage disease - Very rare
S-jögren–Larsson syndrome - Rare