Histo Bodies Buzz Flashcards
Antoni A tissue - ?Description - ?Characteristic in which entitiy
Cellular pattern (spindle cells arranged in stacks with palisading nuclei) with Verocay bodies - Schwannoma
Antoni B tissue - ?Description - ?Characteristic in which entitiy
Hypocellular pattern: loose stroma and few cells - Schwannoma
Asteroid bodies - ?Description - ?Characteristic in which entitiy
Extracellular central spore surrounded by radiating homogenous eosinophilic material - Sporotrichosis (Splendore-Hoeppli phenomenon)
Intracellular stellate eosinophilic inclusion bodies within multinucleated giant cell - ?Description - ?Characteristic in which entitiy
Sarcoidosis, berylliosis, foreign body reaction, etc. -
Banana bodies - ?Description - ?Characteristic in which entitiy
Banana-shaped golden-yellow (ochre) fibers - Ochronosis
Bean bag cells - ?Description - ?Characteristic in which entitiy
Histiocytes showing phagocytosis of lymphocytes, erythrocytes or platelets - Cytophagic histiocytic panniculitis
Birbeck granules - ?Description - ?Characteristic in which entitiy
Tennis racket-shaped or rod-shaped structures within cytoplasm of Langerhans cell seen on EM - Langerhans cell histiocytosis
Caterpillar bodies - ?Description - ?Characteristic in which entitiy
Wavy eosinophilic material in basal epidermal layer or roof of blister - Porphyria cutanea tarda, erythropoietic porphyria
Cholesterol clefts - ?Description - ?Characteristic in which entitiy
Lipid crystals inside adipocytes forming rosettes of needle-like clefts - Sclerema neonatorum, subcutaneous fat necrosis of newborn
Clear needle-shaped spaces (not necessarily in adipocytes) - ?Description - ?Characteristic in which entitiy
Xanthomas, necrobiotic xanthogranuloma -
Colloid bodies (Civatte bodies) - ?Description - ?Characteristic in which entitiy
Eosinophilic homogenous structures (cell remnants) in lower epidermis or papillary dermis - Lichen planus, other interface dermatoses
Corp ronds - ?Description - ?Characteristic in which entitiy
Dyskeratotic acantholytic keratinocytes with round nuclei and perinuclear halo - Darier disease, Hailey-Hailey, Grover’s, warty dyskeratoma
Cowdry Type A inclusion bodies - ?Description - ?Characteristic in which entitiy
Large eosinophilic intranuclear inclusion with surrounding clear halo in infected cells - HSV and VZV infection
Cowdry Type B inclusion bodies - ?Description - ?Characteristic in which entitiy
Intranuclear amorphous bodies surrounded by clear halo in neural cells - Polio
Donovan bodies - ?Description - ?Characteristic in which entitiy
Intracytoplasmic bacteria in infected histiocytes (vacuolated appearance containing bacilli) - Granuloma inguinale
Dutcher bodies - ?Description - ?Characteristic in which entitiy
Eosinophilic intranuclear inclusions of immunoglobulins in malignant plasma cells - Multiple myeloma
Flame figures - ?Description - ?Characteristic in which entitiy
Eosinophilic material (cells and debris) surrounding pink amorphous collagen - Well’s syndrome, arthropod bite, drug reaction
Floret-type giant cell - ?Description - ?Characteristic in which entitiy
Giant cells with eosinophilic cytoplasm and marginally placed nuclei resembling small flower - Pleomorphic lipoma
Globi - ?Description - ?Characteristic in which entitiy
Foamy histiocytes containing clustered bacilli - Lepromatous leprosy
Gamma Favre body - ?Description - ?Characteristic in which entitiy
Large intracytoplasmic basophilic inclusion body - Lymphogranuloma venereum
Gargoyle cells - ?Description - ?Characteristic in which entitiy
Fibroblast with large deposits of mucopolysaccharide (MPS) - MPS storage diseases (ie. Hurler)
Grains - ?Description - ?Characteristic in which entitiy
Basophilic dyskeratotic cells with elongated wavy or ‘grain-shaped’ nuclei in granular layer - Darier disease, Hailey-Hailey, Grover’s, warty dyskeratoma
Guarnieri bodies - ?Description - ?Characteristic in which entitiy
Eosinophilic cytoplasmic inclusions in affected epithelial cells - Vaccinia or smallpox
Henderson-Patterson bodies - ?Description - ?Characteristic in which entitiy
Large eosinophilic cytoplasmic inclusion of viral protein in keratinocytes - Molluscum contagiosum
Kamino bodies - ?Description - ?Characteristic in which entitiy
Eosinophilic amorphous globules (contain basement membrane component) - Spitz nevi
Koilocytes - ?Description - ?Characteristic in which entitiy
Keratinocyte with hyperchromatic nuclei surrounded by perinuclear halo - HPV infection
Langhans giant cells - ?Description - ?Characteristic in which entitiy
Multinucleated giant cell with peripheral nuclei in horseshoe shape - Foreign body reaction, hypersensitivity reaction
Lipofuscin granules - ?Description - ?Characteristic in which entitiy
Lipofuscin yellow-brown granule accumulation in dermal macrophages - Amiodarone pigmentation
Max Joseph space - ?Description - ?Characteristic in which entitiy
Artifactual clefting at dermo-epidermal junction - Lichen planus
Medlar bodies (Copper pennies) - ?Description - ?Characteristic in which entitiy
Thick-walled spherical brown cells - Chromomycosis
Miescher’s radial granuloma - ?Description - ?Characteristic in which entitiy
Nodules containing histiocytes arranged radially around central cleft in interlobular septae - Erythema nodosum
Miescher’s granuloma - ?Description - ?Characteristic in which entitiy
Phagocytosis of dermal elastic fibers by giant cells and histiocytes - Annular elastolytic giant cell granuloma (actinic granuloma)
Michaelis Gutmann bodies - ?Description - ?Characteristic in which entitiy
Concentric basophilic lamellar bodies in foamy macrophages (von Hansemann) in urinary tract - Malakoplakia
Mikulicz cell - ?Description - ?Characteristic in which entitiy
Foamy macrophage containing bacilli - Rhinoscleroma
Mariner’s wheel - ?Description - ?Characteristic in which entitiy
Budding yeast resemble ‘mariner’s wheel’ - Paracoccidiodomycosis
Mulberry cells - ?Description - ?Characteristic in which entitiy
Multiple septations with mulberry-like sporangia - Protothecosis, hibernoma
Munro microabscess - ?Description - ?Characteristic in which entitiy
Small collection of neutrophils within horny layer associated with parakeratosis - Psoriasis
Negri bodies - ?Description - ?Characteristic in which entitiy
Neuronal eosinophilic bodies - Rabies
Pautrier microabscesses - ?Description - ?Characteristic in which entitiy
Collection of atypical T cells within epidermis - Cutaneous T-cell lymphoma
Psammoma body - ?Description - ?Characteristic in which entitiy
Concentrically laminated collection of calcium - Meningioma
Pustulo-ovoid bodies - ?Description - ?Characteristic in which entitiy
Round eosinophilic cytoplasmic inclusion - Granular cell tumor
Rocha-Lima bodies - ?Description - ?Characteristic in which entitiy
Pink-purple cytoplasmic inclusion in endothelial cells - Oroya fever/verruga peruana
Russell bodies - ?Description - ?Characteristic in which entitiy
Eosinophilic immunoglobulin deposits within plasma cell - Rhinoscleroma, granuloma inguinale
Verocay body - ?Description - ?Characteristic in which entitiy
Parallel rows of nuclei surrounded by homogenous eosinophilic material - Schwannoma
Schaumann bodies - ?Description - ?Characteristic in which entitiy
Calcified inclusion from degenerated lysosomes in macrophages - Sarcoidosis
Virchow cells - ?Description - ?Characteristic in which entitiy
Foamy histiocytes containing M. leprae - Lepromatous leprosy
Von Hansemann cells - ?Description - ?Characteristic in which entitiy
Foamy eosinophilic macrophages containing Michaelis Gutmann bodies - Malakoplakia