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Medical Derm Revision > Histo Bodies Buzz > Flashcards

Histo Bodies Buzz Flashcards

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USMLE® Step 1 flashcards Dermatology Board Prep flashcards
1
Q

Antoni A tissue - ?Description - ?Characteristic in which entitiy

A

Cellular pattern (spindle cells arranged in stacks with palisading nuclei) with Verocay bodies - Schwannoma

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2
Q

Antoni B tissue - ?Description - ?Characteristic in which entitiy

A

Hypocellular pattern: loose stroma and few cells - Schwannoma

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3
Q

Asteroid bodies - ?Description - ?Characteristic in which entitiy

A

Extracellular central spore surrounded by radiating homogenous eosinophilic material - Sporotrichosis (Splendore-Hoeppli phenomenon)

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4
Q

Intracellular stellate eosinophilic inclusion bodies within multinucleated giant cell - ?Description - ?Characteristic in which entitiy

A

Sarcoidosis, berylliosis, foreign body reaction, etc. -

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5
Q

Banana bodies - ?Description - ?Characteristic in which entitiy

A

Banana-shaped golden-yellow (ochre) fibers - Ochronosis

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6
Q

Bean bag cells - ?Description - ?Characteristic in which entitiy

A

Histiocytes showing phagocytosis of lymphocytes, erythrocytes or platelets - Cytophagic histiocytic panniculitis

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7
Q

Birbeck granules - ?Description - ?Characteristic in which entitiy

A

Tennis racket-shaped or rod-shaped structures within cytoplasm of Langerhans cell seen on EM - Langerhans cell histiocytosis

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8
Q

Caterpillar bodies - ?Description - ?Characteristic in which entitiy

A

Wavy eosinophilic material in basal epidermal layer or roof of blister - Porphyria cutanea tarda, erythropoietic porphyria

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9
Q

Cholesterol clefts - ?Description - ?Characteristic in which entitiy

A

Lipid crystals inside adipocytes forming rosettes of needle-like clefts - Sclerema neonatorum, subcutaneous fat necrosis of newborn

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10
Q

Clear needle-shaped spaces (not necessarily in adipocytes) - ?Description - ?Characteristic in which entitiy

A

Xanthomas, necrobiotic xanthogranuloma -

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11
Q

Colloid bodies (Civatte bodies) - ?Description - ?Characteristic in which entitiy

A

Eosinophilic homogenous structures (cell remnants) in lower epidermis or papillary dermis - Lichen planus, other interface dermatoses

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12
Q

Corp ronds - ?Description - ?Characteristic in which entitiy

A

Dyskeratotic acantholytic keratinocytes with round nuclei and perinuclear halo - Darier disease, Hailey-Hailey, Grover’s, warty dyskeratoma

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13
Q

Cowdry Type A inclusion bodies - ?Description - ?Characteristic in which entitiy

A

Large eosinophilic intranuclear inclusion with surrounding clear halo in infected cells - HSV and VZV infection

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14
Q

Cowdry Type B inclusion bodies - ?Description - ?Characteristic in which entitiy

A

Intranuclear amorphous bodies surrounded by clear halo in neural cells - Polio

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15
Q

Donovan bodies - ?Description - ?Characteristic in which entitiy

A

Intracytoplasmic bacteria in infected histiocytes (vacuolated appearance containing bacilli) - Granuloma inguinale

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16
Q

Dutcher bodies - ?Description - ?Characteristic in which entitiy

A

Eosinophilic intranuclear inclusions of immunoglobulins in malignant plasma cells - Multiple myeloma

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17
Q

Flame figures - ?Description - ?Characteristic in which entitiy

A

Eosinophilic material (cells and debris) surrounding pink amorphous collagen - Well’s syndrome, arthropod bite, drug reaction

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18
Q

Floret-type giant cell - ?Description - ?Characteristic in which entitiy

A

Giant cells with eosinophilic cytoplasm and marginally placed nuclei resembling small flower - Pleomorphic lipoma

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19
Q

Globi - ?Description - ?Characteristic in which entitiy

A

Foamy histiocytes containing clustered bacilli - Lepromatous leprosy

20
Q

Gamma Favre body - ?Description - ?Characteristic in which entitiy

A

Large intracytoplasmic basophilic inclusion body - Lymphogranuloma venereum

21
Q

Gargoyle cells - ?Description - ?Characteristic in which entitiy

A

Fibroblast with large deposits of mucopolysaccharide (MPS) - MPS storage diseases (ie. Hurler)

22
Q

Grains - ?Description - ?Characteristic in which entitiy

A

Basophilic dyskeratotic cells with elongated wavy or ‘grain-shaped’ nuclei in granular layer - Darier disease, Hailey-Hailey, Grover’s, warty dyskeratoma

23
Q

Guarnieri bodies - ?Description - ?Characteristic in which entitiy

A

Eosinophilic cytoplasmic inclusions in affected epithelial cells - Vaccinia or smallpox

24
Q

Henderson-Patterson bodies - ?Description - ?Characteristic in which entitiy

A

Large eosinophilic cytoplasmic inclusion of viral protein in keratinocytes - Molluscum contagiosum

25
Q

Kamino bodies - ?Description - ?Characteristic in which entitiy

A

Eosinophilic amorphous globules (contain basement membrane component) - Spitz nevi

26
Q

Koilocytes - ?Description - ?Characteristic in which entitiy

A

Keratinocyte with hyperchromatic nuclei surrounded by perinuclear halo - HPV infection

27
Q

Langhans giant cells - ?Description - ?Characteristic in which entitiy

A

Multinucleated giant cell with peripheral nuclei in horseshoe shape - Foreign body reaction, hypersensitivity reaction

28
Q

Lipofuscin granules - ?Description - ?Characteristic in which entitiy

A

Lipofuscin yellow-brown granule accumulation in dermal macrophages - Amiodarone pigmentation

29
Q

Max Joseph space - ?Description - ?Characteristic in which entitiy

A

Artifactual clefting at dermo-epidermal junction - Lichen planus

30
Q

Medlar bodies (Copper pennies) - ?Description - ?Characteristic in which entitiy

A

Thick-walled spherical brown cells - Chromomycosis

31
Q

Miescher’s radial granuloma - ?Description - ?Characteristic in which entitiy

A

Nodules containing histiocytes arranged radially around central cleft in interlobular septae - Erythema nodosum

32
Q

Miescher’s granuloma - ?Description - ?Characteristic in which entitiy

A

Phagocytosis of dermal elastic fibers by giant cells and histiocytes - Annular elastolytic giant cell granuloma (actinic granuloma)

33
Q

Michaelis Gutmann bodies - ?Description - ?Characteristic in which entitiy

A

Concentric basophilic lamellar bodies in foamy macrophages (von Hansemann) in urinary tract - Malakoplakia

34
Q

Mikulicz cell - ?Description - ?Characteristic in which entitiy

A

Foamy macrophage containing bacilli - Rhinoscleroma

35
Q

Mariner’s wheel - ?Description - ?Characteristic in which entitiy

A

Budding yeast resemble ‘mariner’s wheel’ - Paracoccidiodomycosis

36
Q

Mulberry cells - ?Description - ?Characteristic in which entitiy

A

Multiple septations with mulberry-like sporangia - Protothecosis, hibernoma

37
Q

Munro microabscess - ?Description - ?Characteristic in which entitiy

A

Small collection of neutrophils within horny layer associated with parakeratosis - Psoriasis

38
Q

Negri bodies - ?Description - ?Characteristic in which entitiy

A

Neuronal eosinophilic bodies - Rabies

39
Q

Pautrier microabscesses - ?Description - ?Characteristic in which entitiy

A

Collection of atypical T cells within epidermis - Cutaneous T-cell lymphoma

40
Q

Psammoma body - ?Description - ?Characteristic in which entitiy

A

Concentrically laminated collection of calcium - Meningioma

41
Q

Pustulo-ovoid bodies - ?Description - ?Characteristic in which entitiy

A

Round eosinophilic cytoplasmic inclusion - Granular cell tumor

42
Q

Rocha-Lima bodies - ?Description - ?Characteristic in which entitiy

A

Pink-purple cytoplasmic inclusion in endothelial cells - Oroya fever/verruga peruana

43
Q

Russell bodies - ?Description - ?Characteristic in which entitiy

A

Eosinophilic immunoglobulin deposits within plasma cell - Rhinoscleroma, granuloma inguinale

44
Q

Verocay body - ?Description - ?Characteristic in which entitiy

A

Parallel rows of nuclei surrounded by homogenous eosinophilic material - Schwannoma

45
Q

Schaumann bodies - ?Description - ?Characteristic in which entitiy

A

Calcified inclusion from degenerated lysosomes in macrophages - Sarcoidosis

46
Q

Virchow cells - ?Description - ?Characteristic in which entitiy

A

Foamy histiocytes containing M. leprae - Lepromatous leprosy

47
Q

Von Hansemann cells - ?Description - ?Characteristic in which entitiy

A

Foamy eosinophilic macrophages containing Michaelis Gutmann bodies - Malakoplakia

Medical Derm Revision (51 decks)

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