mitosis Flashcards
after replication of the chromosome, each replicated chromosome consists of what?
2 sister chromatids
why is a mitotic spindle apparatus formed during the division process?
so that the chromosomes are divided equally between the new 2 daughter cells
what are the stages of mitotic nuclear division?
prophase, pro-metaphase, metaphase, anaphase, telophase, PPMAT
what happens after PPMAT?
Cytokinesis
during nuclear division, what are chromosomes separated by?
microtubules
what is the kinetchore there for?
for the kinetchore microtubules to grab hold of
what is the dna molecule wrapped around?
many histones
what are the 3 types of microtubules?
astral, kinetchore, polar
what is the centrosome?
microtubule organising centre, MTOC
what do polar microtubules do?
they dont make contact with eachother, if they meet one coming the other way then they start to bond together to form a spindle apparatus
what does each centrosome contain?
a pair of centrioles
what happens in interphase?
everything including chromosomes and centrosomes have replicated
what happens in prophase?
chromosomes start to condense, the sister chromatids become visible, mitotic spindle starts to form outside the nucleus, nuclear envelope starts to dissapear. centrosomes move to opposite poles of the cell
what happens in pro-metaphase?
nuclear envelope has broken down into small vesicles.
mitotic spindle microtubules enter the nuclear region
microtubules attach to kinethcores
what happens in metaphase?
chromosomes are held in tension at the metaphase plate halfway between the poles.
chromosomes attached to kinetochore microtubules
