GI system Flashcards
what is the most convenient and cost-effective route of adminstration?
oral administration
what are the functions of the GI system?
digests food,absorption of nutrients and drugs, elimination
what are the regions of the GI tract?
mouth, esophagus, stomach, small intestine
what are the accessory organs?
salivary glands, liver, gall bladder, pancreas
what is peristalsis?
series of wave-like muscle contractions that moves food to different processing stations in the digestive tract.
what is gastric emptying?
moving food to small intestine
what delays gastric emptying?
presence of food in the stomach, and affects the rate of aborption
what are the factors that affect the gastric emptying time?
volume of meal, Kcal contents, fat content, protein content, liquid/solid state, sex, disease states
what are the components of the small intestine?
duodenum, jejunum, and ileum
what is chyme?
the pulpy acidic fluid which passes from the stomach to the small intestine, consisting of gastric juices and partly digested food.
what is the role of the small intestine?
completes digestion of nutrients in chyme, major site of absorption of different nutrients, site of absorption of orally administered drugs, site of first pass metabolism
why is the surface area of the small intestine so large?
due to the vili and microvilli
blood perfusing intestine goes into liver via…
hepatic portal vein
after passing through liver, drug goes where?
into systemic circulation
what is coeliac disease?
lifelong autoimmune condition which is triggered by an intolerance to gluten.
disorder to the immune system.
causes disfunction of villi in small intestine
