Miscellaneous, Acid Fast bacilli, Anaerobic bacteria Flashcards
-produce Much granules
-resistant to decolorization
-can ‘clump’
-‘Gram neutral and Gram ghosts’
-incomplete staining= beaded appearance
mycobacteria
-beaded rods, X, V, Y and L formation
-‘cauliflower colonies’ with cording
-has CORD factor
m. tuberculosis/ KOCH bacillus
-attenuated strain used for vaccination in newborns of mycobacterium
m. bovis
mycobacterium vaccine from attenuated strain of b. bovis
bacille-calmette-guerin
-associated with human cases of TB in tropical africa
-requires spoligotyping
m. africanum
-smooth strain of m. tuberculosis
-first human isolate from cervical lymph node, from aids patients
m. canetti
isolated from TB patients in both immunocompetent and immunocompromised individuals
m. microti
-disease of respiratory tract
-airborne 1-5um
-also known as ‘CONSUMPTION’
tuberculosis
when a tubercle turns to a cheeselike consistency called
caseous lesion
if causeous lesions calcify, they are termed as - observed in chest xray
ghon complexes
organization of lympohocytes, macrophage, fibroblast
granuloma
-AKA. TUBERCULOSIS spondylitIS OR SKELETAL TB
-tb to spinal vertebrae
pott’s disease
-extrapulmonary TB
-after primary pulmonary disease
millary TB
-acquired by spontaneous mutation of inappropriate use of antimicrobial agents to treat M tuberculosis
MDR-TN
multidrug resistant m. tuberculosis
MDTRB
without previous history of TB
primary MDR-TB
MDRTB
defined as resistance to drugs
extensively drug resistant TB/ XDR-TB
ranyoun’s classification of nontuberculous mycobacteria
not pigmented unless exposed to light
-dark: cream or buff
-light: orange/yellow
photochromogens
ranyoun’s classification of nontuberculous mycobacteria
pigmented both in dark and light
scotochromogens
ranyoun’s classification of nontuberculous mycobacteria
non-pigmented both in dark and light
nonphotochromogens
ranyoun’s classification of nontuberculous mycobacteria
pigment variation
3-7 days growth rate
rapid growers
contributes greatly to incidence of NTM disease
AIDS
most common NTM causing tuberculosis
m. avium
m. avium
wood pigeon bacillus
m. avium. silvaticum
NTM that cause disease in poultry and swine
M. avium
-causative agent of JOHNE’S DISEASE
-from patients with chron’s disease
-very slow grower
m. avium. paratuberculosis
-second cause of NTM lung disease
-AKA. YELLOW BACILLUS
-seen as ‘SHEPHERD’S CROOK’
-dark red crystal of 10b carotene
m. kansasii
-disease of fish isolated from aquarium
-SWIMMING POOL GRANULOMA
m. marinum
-3rd most common mycobacterium after m. tuberculosis and m. leprae
-cause of BURULI cancer
m. ulcerans
-seen as a problem in preparation of bacteriologic smears
-aka. TAP WATER BACILLUS
m. gordonae
-recovered from hot and cold tap water- water storage tanks
-from african toad
-BIRD’S NEST with sticklike projections
m. xenopi
aka. RADISH BACILLUS
m. terrae
mycobacterium
most common rapidly growing bacteria- localized cutaneous infections
m. fortuitum
mycobacterium
-associated with disseminated cutaneous infections
-outbreak with administration of DPT-polio vaccines
m. chelonae
mycobacterium
-causes bone infections
-branching y shaped forms
m. smegmatis
BSC for diagnosis of NTM
class 2-3
-specimen used to recover mycobacteria that may have been swallowed during the night
-detection in children
gastric lavage
specimen of choice for detecting NTM, obtained when collecting sputum is not possible
bronchoscopy specimens
specimen to identify patients who may be at risk of deceloping m. avium
fecal specimens
grading of sputum specimens:
for scoring sputum
bartlett’s
grading of sputum specimens:
for contaminataion assessment
murray-washington
grading of sputum specimens:
emphasize ratio between SECs and PMNs
heinemans
most commonly used egg based medium
lawenstain jensen
recovery of mycobacterua from heavily contaminated spx medium
petragani medium
medium for m. avium
wallenstein
test that indicates m. tuberculosis
mantoux test
test for immune response to bacteriual antigen mycobacterium
tuberculin test
most commonly used biochemical test for identification of MTB
niacin test
-found in schwann cells
-HANSEN’s bacillus
-CIGAR POCKET/ POCKET FENCE
m. leprae
2 forms of leprosy:
localized/ neural leprosy/ benign
tuberculoid
2 forms of leprosy:
disseminated/progressive/ malignant
lepromatous
hansens disease, scaly scabby and rough
leprosy
marker for malignany in GI tract
smooth swarming
c. septicum
only urease + clostridia
c. sordelli
-GAS GANGRENE BACILLUS
-clostridum welchii
-BOXCAR shaped
-STORMY FERMENTATION OF MILK
c. perfrigens
-eating sore
-desctruction of muscles
gas gangrene/myconecrosis
-PIG-BEL
ingestion of entrotoxin
food prisoning/ enteritis necrotans
2 types of food poisoning:
mild and self limiting
type a food poisoning
2 types of food poisoning:
serious but rare
type c food poisoning
-TRACK HEAD BACILLUS
-DRUMSTICK/LOLLIPOP/TENNIS RACKET
clostridium tetani
lockjaw
trismus
distorted grin
risus sardonicus
-CANNED GOOD BACILLUS
-potential agent of bioterrorism
-contains most potent toxin known to man
-produce paralysis and death
c. botulinum
most potent toxin known to man, has 7 types
cleaves synaptic cells
botulism toxin
types of botulism toxin associated with human infections
A, B, E
toxin type -, used to treat strabismus/ wandering eye and beauty enhancer
A
-ingestion from honey or breast feeding, infection
-FLOPPY BABY SYNDROME
infant botulism
most common cause of antibiotic associated diarrhea
infection control DILEMMA
-HORSE STABLE/ BARNYARD COLOR
c. difficile
definitive identification test for c. botulinum
mouse neutralization test
gold standard test for detection of c. difficile
cell structure cytoxicity test
differentiate c. bifermentans and c. sordellil
spot indole test
anaerobic nonsporeforming bacilli and cocci
spiderlike/ wooly appearance
molar tooth
actinomyces
anaerobic nonsporeforming bacilli and cocci
safety pin appearance
bacteroides fragilis
anaerobic nonsporeforming bacilli and cocci
forked ends/ dog bones
bifibacterium
anaerobic nonsporeforming bacilli and cocci
medusa head
c. septicum
anaerobic nonsporeforming bacilli and cocci
segull wing shape
eubacterium
anaerobic nonsporeforming bacilli and cocci
breadcrumbs like
fusobacyterium
anaerobic nonsporeforming bacilli and cocci
raspberry like
leptotrichia
most commonly isolated anaerobes from blood culture
bacteroides fragilis
most common cause of actinomyces
actinomyces isaraelli
cotains sulfur granules clinical infx
actinomycosis
-RAT BITE FEVER
-HAVERHILL FEVER
-L FORMS
streptobacillus monoliformis
-NECKLACE LIKE ARRANGEMENT
-FRIED EGG
-FLUFF BALLS
streptobacillus monoliformis
-rat bite fever refereed as SODOLU
spirillum minus/minor
etiologic agent of bacterial vaginosis
gardnerella vaginalis
bacterial vaginosis= gardnerella vaginalis
test: clue cells
direct saline
bacterial vaginosis= gardnerella vaginalis
test: fishy amine
whiff/ KOH
etiologic agent of granuloma inguinale or donovanosis
calymmatobacterium granulomatis
-resembles HACEK
-atrichous bacteria with GLIDING MOTILITY
capnocytophaga