Misc Flashcards

1
Q

hyperplasia definition

A

increase in cell number

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2
Q

hypertrophy definition

A

increase in cell size

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3
Q

atrophy definition

A

decrease in cell size

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4
Q

metaplasia definition

A

reversible change in cell type

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5
Q

neoplasia definition

A

new cell growth

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6
Q

dysplasia definition

A

benign/malignant disordered growth

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7
Q

apoptosis definition

A

unprogrammed cell death

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8
Q

what is N0 in TNM staging

A

no node involvement

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9
Q

what is N1 in TNM staging

A

1-3 node involvement

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10
Q

what is N2 in TNM staging

A

4+ node involvement

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11
Q

what is an acrocentric chromosome

when do they occur

A

has a long arm and a short arm

common in cancer

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12
Q

what is a mendelian disease

are they generally serious or not

are they common or rare

A

purely genetic

serious

rare

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13
Q

what is a multifactorial disease

are they generally serious or not

are they common or rare

A

mixture of genetic and environmental factors

not

common

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14
Q

where do you get mitochondrial DNA

A

from your mother

M itochondiral = M um/M aternal

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15
Q

trisomy 21

A

downs syndrome

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16
Q

trisomy 14

A

miscarriage

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17
Q

trisomy 18

A

Edwards syndrome

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18
Q

22q11 deletion

A

digeorge syndrome

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19
Q

45X or XO

A

turners syndrome

20
Q

47XXX

A

triple X

21
Q

47XXY

A

klinefelters

22
Q

components of the innate immune response (3)

A

macrophages
mast cells
NK cells

23
Q

components of the adaptive immune response (2)

A

B cells

T cells

24
Q

what are NK cells

A

large granular lymphocytes

25
Q

which Ig is found in breast milk and saliva

A

IgA

26
Q

which Ig is most commonly produced

A

IgA

27
Q

which Ig is most abundant in the body

A

IgG

28
Q

which Ig is involved in allergic responses

A

IgE

29
Q

which Ig is involved in mast cell activation

A

IgE

bc its the one involved in allergic responses

30
Q

which Ig is involved in neonatal immunity

A

IgA

31
Q

which Ig is the largest

A

IgM

32
Q

which Ig is present first in infection (and hence measured in primary hormonal immune response)

A

IgM

33
Q

which Ig is an ‘antigen cell receptor’

A

IgD

34
Q

which Ig is a pentamer

A

IgM

35
Q

which germ layer do organs come from

A

mesoderm

36
Q

which germ layer does the lining of the GI and resp tract come from

A

endoderm

37
Q

which germ layer does the skin and nerves come from

A

ectoderm

38
Q

energy supply 0-4 secs

A

ATP

39
Q

energy supply 4-15 secs

A

phosphocreatinine

40
Q

energy supply 15 secs - 4 mins

A

free circulating glucose

41
Q

energy supply 4-77 mins

A

glycogen stores

42
Q

energy supply > 4 days

A

fat stores

43
Q

which type of white blood cell has a kidney shaped nucleus

A

monocyte

mono = one nucleus (most are bilobed)

44
Q

which type of white blood cell has a large circular nucleus

A

lymphocyte

Lymphocyte = Large nucleus

45
Q

which type of white blood cell has pink dots in front of a bilobed nucleus

A

eosinophils

46
Q

which type of white blood cell can you not really see the nucleus in (its a bilobed nucleus)

A

basophil

Basophil = looks Blotchy

47
Q

which type of white blood cell has a multilobed nucleus

A

neutrophil