Migraine Flashcards
1
Q
How do you treat an estrogen related migraine?
A
Several days of high exposure to estrogen
2
Q
What does Neuropeptide do?
A
Causes inflammation and thus a migraine
3
Q
What inhibits neuropeptide release?
A
Activation of 5-HT1d receptor
4
Q
How does migraine effect PAG?
A
Causes irreversible damage in the center of the brains neural network.
Ex: iron deposition and free radical damage
5
Q
What doe GABA inhibit?
A
Pain
6
Q
How does Valproic acid work?
A
Inhibits GABA amino transferase thus preventing the breakdown of GABA
7
Q
Triptans are agonists of what?
A
5-HT. They prevent the release of neuropeptides and thus reduce moderate- severe migraines
8
Q
Which triptan is most effective at preventing a relapse?
A
Almotriptan
