MIDTERM blood and hemopoiesis Flashcards
Temperature of blood
30° or 100 Fahrenheit
pH level of blood
7.35 to 7. 45
Color of oxygenated blood
Bright red
Color of deoxygenated blood
Dark red
Blood volume of adult male
5-6 L or 1.5 gallons
Blood volume of adult female
4 to 5 L or 1.2 gallons
Adult female has larger body mass than adult male
False
Three components of centrifugated blood
Plasma, Buffy coat, RBC
plasma percentage in centrifugated blood
55%
Percentage of buffy coat
1%
Red blood cells percentage In a centrifugadated blood
45%
Buffy coat consist of
Plasma and platelets
WBCs that exhibits phagocytic properties
Neutrophils, monocytes, eosinophils
Three blood function
Transportation, protection, regulation
Blood transport what
Gas, nutrients, hormones, waste products
Blood protect what
From injury and trauma, and against disease which are WBC and blood protein
Blood regulates
Homeostasis, pH, temperature, osmotic pressure
Volume of RBC in male
4.5 to 5.9×10 raised to 12 per liter
Volume of RBC in female
4.1- 5.1×10 raised to 12 per liters
Volume of WBC in female and male
4.4 - 11.3×10 raised to nine per liter
Volume of platelets in male and female
150-450x10 ^9 per liter
It is a type of protein that maintains normal osmotic pressure
albumin
It is a type of protein that has a precursor of the fibrin
fibrinogen
It is a Globulin that transport of bilirubin, lipids and steroids
Alpha globulin
It is a type of globulin that is associated with the transport of iron and copper
Beta globulin
It is a type of globulin that acts as antibodies which attacks foreign substances
gamma globulin
whole blood percent
8%
Other fluids and tissues percent
92%
proteins percent
6-7%
Formed elements volume
45%
Platelets has how much microliter
150,000 to 400,000
water percent
91.5%
White blood cells has microliter of
5000 to 10,000 µL
Red blood cells has
4.8-5.4 million microliter
Formed elements contains
Platelets white blood cells and red blood cells
White blood cells contains
Neutrophils eosinophils basophils lymphocytes and monocytes
neutrophils percentage
60-70%
Lymphocyte percentage
20 to 25%
Monocytes percentage
3-8%
eosinophils percentage
2-4%
Basophils percentage
0.5 to 1.0%
Whole blood contains
Blood plasma and formed elements
Blood plasma contains
Proteins, water and other solutes
Other solutes percentage
1.5%
Other solutes contains
Electrolytes, nutrients, gases, regulatory substances, waste products
Proteins contains
albumins, globulin, fibrinogen, all others
protein is composed of
Carbohydrates lipids vitamins hormones and enzyme
Lifespan of WBC
9 to 10 days
Lifespan of RBC
120 days
Blood components that is responsible for the transport of respiratory gases
erythrocytes or RBC
It is a blood component that contributes to homeostasis and or plugging/ clotting
Platelets
Percentage of albumin
54%
Percentage of globulins
38%
fibrinogen percentage
7%
All others percentage
1%
Serum and plasma are both fluid portion of blood
True
It is from clotted blood
Serum
It is from anticoagulated blood or un clotted blood
Plasma
It is a blood component that has no clotting factors because it is used up in the clotting process
Serum
It is a fluid portion of blood that has clotting factors
Plasma
ForMation of RBC
erythropoeisis
plts formation
thrombopoeisis
WBC formation
leukopoeisis
Production of granulocytes
Granulopoeisis
Production of lymphocytes
lymphopoeisis
Lymphocytes consist what cell
t-cells, b-cells and nk cells
t-cell mature in
thymus
blood cells mature in
bone marrow
Two types of maturation
synchronous maturation and asynchronous Maturation
It is a type of maturation where there is a concomitant, coordinated and parallel development of nucleus and cytoplasm
Synchronous maturation
It is a type of maturation that is abnormal development of blood cells were the rate of maturation of the nuclues and cytoplasm the first
Asynchronous maturation
Two phase of intrauterine phase
mesoblastic/megaloblastic phase and mesoblastic period
What phase if the chief site is yolk sac
Megaloblastic phase
it is where the blood islands formed
mesoblastic/megaloblastic phase
Blood islands is also called
Mesodermal cells
This phase is detected 19th to 20th day of gestation
Mesoblastic or megaloblastic phase
Megaloblastic phase remain active in what week
8-12th week
Primitive erythroblast is also called
Nucleated RBC
primitive erythroblast is also known as
megaloblast of ehrlich
phase where embryonal hemoglobin is synthesized
Mesoblastic period
phase were primitive endothelial cells and vascular system formed
mesoblastic period
phase where leukopoiesis and megakaryopeisis is located
mesoblastic period
3 types of embryonic hemoglobin
gower 1, gower 2 and portland
globulin chains of gower 1
2 zeta and 2 epsilon
globulin chains of gower 2
2 alpha and 2 epsilon
globulin chains of portland
2 zeta and 2 gamma
Three phases of intraunterine phase
Mesoblastic or megaloblastic phase, hepatic phase, myleloid or medullary phase
Chief site in hepatic phase
liver
peak activity of hepatic phase
3rd or 4th month
peak activity in spleen
4th-7th month
peak activity in thymus and lymph nodes
4th month
It is considered as erythroid organ
liver
globulin chain of Hbf
2 alpha and 2 gamma
phase where fetal hb produce
hepatic phase
chief site is bone marrow
myeloid or medullary phase
It is a site for blood cell production where bone cavities appears
Bone marrow
this phase starts in the 5 months of fetal life
myeloid or medullary phase
Hb A production starts
myeloid or medullary phase
adult hb globulin chain
2 alpha and 2 beta
Hb A2 globulin chain
2 alpha and 2 delta
months of prod of granulopoeisis
2nd month
months of prod of megakaryopoeisis
2nd month
months of prod of lymphopoeisis
4th month
month of prod of monopoeisis
5th month
