Midterm Flashcards
Primary Hemostasis is characterized as (3) events
- Vascular constriction 2. Platelet Aggregation 3. Soft aggregate plug
During primary hemostasis, adhesion occurs when BLANKK attaches to the sub endothelium.
Von willebrand factor vWf allows glycoproteins to adhere to the sub endothelium
Primary hemostasis has a BLANKKK time interval, where as Secondary hemostasis has BLANKK time interval.
Primary=Short lived 20 seconds after injury
Secondary=Long lived
Secondary hemostasis is responsible for (2) events
stabilizing the soft clot and maintaining vasoconstriction
Vasoconstriction is maintained through the platelet secretion of …. (3)
Serotonin, thromboxane, and prostaglandin
As fibrin sets up into a clot, BLANKKK is deposited in to the forming clot until it is activated into plasmin.
Plasminogen
Plasmin is a
fibrinolytic enzyme that degrades fibrin to remove the clot.
Bleeding Time BT is a BLANKKK test
Platelet Function test
Bleeding time is (dependent or independent) on the coagulation
independent, platelet plug will form regardless of fibrin formation
How will the bleeding time change during thrombocytopenia?
it will be prolonged due to a decreased platelet number
What are the two methods of performing a BT test?
Duke method-Stab method to ear lobe
AND
Ivy Bleeding TIme-incision to the forearm