Clin Path Final Flashcards
RA Essentials of Dx
Insidious Onset, Morning Stiffness, P in affected jts, symettrical, small jts of hand and feet, RA nodules, Anti CCP, RF present, extra-articular manifestations
SLE def
A chonic inflammatory disease in which there is production of antibodies, to components of cells of various structures (jts, kidneys, serous surfaces)
What race is most common with SLE?
African american
What gender is most common in SLE?
Female
11 clinical trials of SLE?
Rash: Malar, discoid, photosensitivity,
Oral lesions, Arthritis, Pleuritis, Pericarditis, Seizures, Proteinuria and Cellular casts, hematology, ANA, Anti-native DNA, Anti-SM
SLE Essentials of dx
young women, rash over sunexposed areas, jt sxs, multi systems, anemia, leukopenia, thrombocytopenia, glomerulonephtritis, CNS disease, antiphospholipid antibodies, ANA, anti natie DNA, antibodies, low serum complement levels.
Systemic Sclerosis Limited= BLANKK syndrome
Crest Syndrome
C: R: E: S: T:
Calcinosis cutis, reynauds, esophageal dysfunction, sclerodactyly, talangiectasia
Systemic Sclerosis Essentials of dx
Limited vs Diffuse, Reynauds Phenomenom and ANA in all patients, systemic features: GERD, hypomotility of GI, Pulmonary fibrosis and hypertension, AND renal involvement.
Idiopathic Inflammatory myopathies Essentials of Dx
Bi Prox mscl weakness, cutaneous w dermato, creatine kinase, mscl biopsy, EMG MRI,, malignancy in dermato
Sjogrens syndrome Essentials of dx
women are 90%, avg age 50, dryness of eyes and mouth, Rheumatoid factor, lymphoma
PMR and GCA Essentials of Diagnosis
Age over 50, GCA visual abnormalities, PMR is pain and sttiffness in shoulders and hips