Midterm 2 - Tobacco Flashcards
Nicotine
Addictive CNS Stimulant
Nicotine can be as addictive as heroin or cocaine? T or F
True
What specific genes affect nicotine metabolism? And what responses do they give?
CYP2A6
- Influences the way in which nicotine is metabolized
- People with slow CYP2A6, nicotine remains in their system longer
DRD2
- Associated with neurotransmitter dopamine
What age do people typically start smoking/chewing
13 - Smoking
10 - Chewing
What is cigarette tar?
Condensed particles in cigarettes that forms a brown sticky mass
What are carcinogens and cocarcinogens?
Carcinogens - Cancer causing agent
Cocarcinogens - Assists
Both - Benzo(a)pyrene and Urethane
How does carbon monoxide affect the body?
Displaces oxygen in red blood cells
Top 3 reasons for death among smokes
- Lung cancer
- Ischemic heart disease
- Chronic Obstructive Pulmonary Disease (COPD)
Immediate physiological effects of nicotine on the body
Increased heart rate and blood pressure
Air sacks where exchange between o2 and co2 take place
Alveoli
Cells container small hair-life projections
Cilia
How does cilia help to filter the air we breathe?
Helps to push the mucus up and out
What are some reasons smoking may cause cancer?
Cigarette smoke slows and stops the action of cilia (cilia helps filter lungs)
Smoking makes macrophates work less effectively
Environmental smoke is the same as
Second-hand smoke
Smoke that is inhaled by a smoker and then exhaled into the environment is
Mainstream smoke
Smoke that comes from the burning end of a cigarette, cigar or pipe is called
Sidestream smoke
Name some pros of vapes/electronic cigarettes
No tobacco
Adjustable nicotine levels
Less risk of potential disease
Propylene glycol
Name some cons of vapes/electronic cigarettes
Still contain carcinogens Nictone still addictive Many have propylene glycol Bacterial clearance in lung (risk of bacterial pneumonia) Increase risk of "popcorn lung"
What types of tobacco have an increased risk for oral cancer?
Chewing tobacco
Cigar and Pipes
Hookah
Plaque build up is
Ischemia
Persistent inflammation of the bronchial tubes
Chronic Bronchitis
Fatty-wax substance, LDL cholesterol
Plaque
Plaque build up in the arteries
Atherosclerosis
Atheroslerosis in the C.A.
Coronary Artery Disease (CAD)