midterm 2- anemia

Question 1

2 conditions with decr MCV

Answer 1

thalassemia minor
iron def

(incr MCV: B12, folate, hypothyroidism, liver )

Question 2

mc hematological disorder

Answer 2

Iron deficiency anemia

Question 3

anti-intrinsic AB

(+) schilling’s test

Answer 3

pernicious anemia

Question 4

decr:

• ferritin
• %transferrin saturation

incr:
- TIBC
- RBW

Answer 4

Iron- deficiency anemia

Question 5

Incr: RBC
Decr: MCV

Normal:

• ferretin
• TIBC

genetic counsiling

Answer 5

thalassemia Minor

child would be MAJOR

Question 6

classification of anemia in 75% of chronic dz’s

Answer 6

normocytic, normochromic

Question 7

macrocytic

numbness and tingling (myelin sythesis)
- swollen tongue

lab:
- high methylmalonate and homocysteine

pop:
- tapeworm
- meds
- vegans

Answer 7

Vit B 12 def

tx: B12 injections

Question 8

macrocytic

elevated MCV
decr RBC folate

pop: alcoholics and pregos

Answer 8

Folic acid deficiency

Question 9

howell jolly bodies

Answer 9

sickle cell anemia

autosomal recessive

Question 10

(-) Coombs test

abn RBC structure (autosomal dominent)

Answer 10

hereditary spherocytosis

Question 11

formation of Hg S

cc:
- jaundice
- splenomegaly
- poor healing of tibial ulcers
- 13/10 pn

Answer 11

sickle cell anemia

Question 12

(+) Coombs test

Answer 12

AI hemolytic anemia

Question 13

anemia secondary to chronic dz

IgG coats RBC–> turns them into sphrocytes to macrophage in the spleen

evan’s sx: thrombocytopenia

(+) coombs test

Answer 13

AI hemolytic anemia

Question 14

pancytopenia: decr WBC, RBC, and plateletes

Answer 14

aplastic anemia