Midquarter 1 Review Flashcards
Which ANS neurons are cholinergic?
All preganglionic (P & S)
Sympathetic post to most sweat glands
All parasympathetic post
Where are nicotinic receptors found?
Chromaffin cells (modified postganglionic sympathetic neurons)
Motor end plate of NMJ (somatic NS)
Sympathetic & parasympathetic postganglionic neurons (dendrites & cell bodies)
Where are muscarinic receptors found?
Smooth mm
Cardiac mm
Glands
What are some symptoms of muscarine poisoning?
Excessive gland secretions
Excessive sweating
Smooth mm stimulation (diarrhea)
What pathway does this describe?
Nicotinic > adrenergic > effector
Sympathetic pathway to most effectors (except many sweat glands)
What pathway(s) does this describe? Nicotinic > muscarinic > effector
Sympathetic to most sweat glands and all parasympathetic pathways.
Nicotinic receptors always result in ____
Excitation
Muscarinic receptor stimulation always results in…
either excitation or inhibition
NE receptor stimulation results in…
either excitation or inhibition of effector cell
When is NE a hormone vs. a neurotransmitter?
hormone when released by chromaffin cells
NT when released by sympathetic postganglionic neurons
Activation of alpha 1 & beta 1 receptors results in…
excitation
Activation of alpha 2 & beta 2 receptors results in…
inhibition
Beta 3 receptors are only present in…
brown fat
Adrenergic receptors can either be ___ or ___
alpha or beta receptors
Cholinergic receptors can either be ___ or ___
nicotinic or muscarinic
True or false: most cells have both alpha or beta receptors
false, most have either or, not both
some visceral effectors have both
True or false: E stimulates alpha receptors more strongly than beta receptors
false, that’s NE.
EPI stimulates both equally
Two enzymes that can degrade NE in the liver include…
COMT and MAO