Class 3 - Neurotransmitters & Receptors Flashcards
Which ANS neurons are cholinergic?
- all sympathetic and parasympathetic preganglionic, and parasympathetic postganglionic
- sympathetic postganglionic to most sweat glands
Nicotinic receptors are found in….
chromaffin cells
motor end plate of NMJ
plasma membrane of dendrites and cell bodies of SNS & PNS postganglionic neurons (receiving end, not transmitting end)
3 locations muscarinic receptors are found:
smooth muscle
cardiac muscle
glands
Nicotinic receptor stimulation ONLY results in __ of the postsynaptic cell
excitation
Skeletal muscle fibres contain ___ receptors
nicotinic (ACh)
T/F: muscarinic receptor stimulation may cause excitation OR inhibition.
T
When NE is released from chromaffin cells, it’s considered a ___
hormone
Alpha 1 & Beta 1 receptor stimulation will cause __ of effector tissues
excitation
Alpha 2 & Beta 2 receptor stimulation will cause __ of effector tissues
inhibition
T/F: most cells contain both alpha and beta receptors.
FALSE, most contain either/or. Some visceral effectors have both.
__ stimulates alpha receptors more strongly than beta receptors
NE
T/F: Epinephrine is equally potent to both alpha and beta receptors.
true
Sympathomimetic drugs have what function?
mimic sympathetic NS functions
Propranolol treats HBP by…
blocking beta receptors to prevent their activation by NE and E