Microman

Question 1

What is the treatment for Strep. viridans infective endocarditis and who gets it?

Answer 1

IV amoxicillin + gentamicin

Own valve endocarditis

Question 2

What is the treatment for Staph aureus endocarditis and who gets it?

Answer 2

IV flucloxacillin

IV drug users

Question 3

What is the treatment for Staph epidermidis endocarditis and who gets it?

Answer 3

IV Vancomycin + gentamicin, PO rifampicin (when switching from IV to oral)
Prosthetic valve patients

Question 4

What bacteria are associated with gut bound endocarditis and what is their treatment?

Answer 4

Enterococcus faecalis + Strep bouis
Amoxicillin
or
IV vancomycin + gentamicin

Question 5

What is the cut off between mild to moderate and severe community acquired pneumonia and what is the treatment for each?

Answer 5

Mild/mod = CURB65 0-2 = amoxicillin
Severe = 3-5 = Co-amoxiclav + doxycycline
Severe + ITU = Co-amoxiclav + clarithromycin

Question 6

What is the treatment for non-severe and severe hospital acquired pneumonia?

Answer 6

Non-severe: amoxicillin + metronidazole

Severe: amoxicillin, metronidazole + gentamicin

Question 7

What are the first and second line treatments for a COPD exacerbation?

Answer 7

First: amoxicillin
Second: doxycycline

Question 8

What is the differentiation between severe and non-severe C. diff infection and what is the treatment of each?

Answer 8

Non-severe (diarrhoea without other symptoms): PO metronidazole
Severe (Alb <3g/dL, WBC >15000 + abdo tenderness): Vancomycin + metronidazole

Question 9

How is peritonitis or any other abdominal infection treated (include if penicillin allergy) and what is the step down treatment for these?

Answer 9

Normal: IV amoxicillin, gentamicin + metronidazole
Penicillin allergy: vancomycin, gentamicin + metronidazole
Step down treatment: co-trimoxazole + metronidazole

Question 10

What is the treatment for spontaneous bacterial peritonitis in mild and severe disease?

Answer 10

Mild: PO co-trimoxazole
Severe: IV piperacillin