Microcytic Anaemia

Question 1

Cytokine driven inhibition of red cell production

Answer 1

Anaemia of Chronic Disease
Ferritin is high to starve bacteria of Fe
In renal failure driven by EPO deficiency

Question 2

Ineffective eryrthopoiesis leading to iron loading causing haemosiderosis

Answer 2

Sideroblastic Anaemia

Endocrine, liver and cardiac damage

Question 3

Classifications of Iron-Deficiency Anaemia

Answer 3

Blood Loss - GI Loss
Increased Utilisation - Pregnancy/Lactation, Growth
Decreased Intake - Prematurity, Diet
Decreased Absorption - Coeliac, Post-Gastric Surgery
Intravascular Haemolysis - Microangiopathic, Haemolytic Anaemia, PNH

Question 4

Side Effects of Fe Tablets

Answer 4

Nausea
Abdominal discomfort
Diarrhea/constipation
Black stools

Question 5

Iron Low
TIBC High
Ferritin Low

Answer 5

Fe Deficiency Anaemia

Question 6

Iron Low
TIBC Low
Ferritin High

Answer 6

Anaemia Chronic Disease

Question 7

Iron High
TIBC Low
Ferritin High

Answer 7

Chronic Haemolysis

Question 8

Iron High
TIBC Low or Normal
Ferritin High

Answer 8

Haemochromatosis

Question 9

Iron High
TIBC High
Ferritin Normal

Answer 9

Pregnancy

Question 10

Iron High
TIBC Normal
Ferritn High

Answer 10

Sideroblastic Anaemia