Haemolytic Anaemias 1 Flashcards
1
Q
Definition
A
Breakdown of RBCs before their normal lifespan of 120 days
2
Q
Increased unconjugated billirubin
A
All
3
Q
Increased Urobilinogen
A
All
4
Q
Increased LDH
A
All
5
Q
Reticulocytosis
A
All
6
Q
Pigmented gallstones
A
All
7
Q
Increased free plasma Hb
A
Intravascular
8
Q
Reduced haptoglobin
A
Intravascular
9
Q
Haemoglobinuria (dark red urine)
A
Intravascular
10
Q
Methaemalbuminaemia (Haem+Albumin in blood)
A
Intravascular
11
Q
Splenomegaly
A
Extravascular
12
Q
Hereditary Spherocytosis
A
Membrane Defect
13
Q
Hereditary Ellptocytosis
A
Membrane Defect
14
Q
G6PD Deficiency
A
Enzyme Defect
15
Q
Pyruvate Kinase Deficiency
A
Enzyme Defect
16
Q
Sickle Cell Disease
A
Haemoglobinopathies
17
Q
Thalassaemias
A
Haemoglobinopathies
18
Q
Immune
A
Autoimmune - Hot/Cold
Alloimmune - Haemolytic Transfusion Reaction
19
Q
Non-Immune
A
Mechanical e.g. Metal Valves, Trauma
PNH, MAHA
Infections
Drugs
