Coagulation Cascade Flashcards
1
Q
3 physiological reactions to injury?
A
Blood Vessel Constriction
Collagen - Platelet Aggregation
Tissue Factor - Coagulation Cascade
2
Q
4 Phases of Coagulation Cascade
A
Initiation - Amplification - Propagation and Thrombin burst - Stable clot
3
Q
4 Inhibitors of Coagulation Cascade
A
Tissue factor pathway inhibitor
Protein C
Protein S
Antithrombin III
4
Q
First factor of Intrinsic Pathway
A
12
5
Q
Measure of Intrinsic Pathway
A
Activated Partial Thromboplastin Time
Monitoring Heparin therapy
Next factor starts with last letter of previous factor
6
Q
First factor of Extrinsic Pathway
A
7
7
Q
Measure of Extrinsic Pathway
A
Prothrombin Time
Monitoring Warfarin Therapy
8
Q
Start of Common Pathway
A
Activated factor 5
9
Q
Measure of Common Pathway
A
Thrombin Time
