Microcirculation Flashcards
function as pressure reservoirs; direct blood to diff areas of body, from heart into pulmonary trunk and aorta; low-resistance vessels; blood press changes very little
arteries
high resistance vessels; regulate resistance within the circuits; regulate blood flow to the organs
arterioles
volume reservoirs; majority of blood is located here
venules and veins
located in almost all tissues; just wide enough to accommodate a red blood cell; sites of exchange bw the blood plasma and the ISF
capillaries
capillaries consist of a single layer of cells called
endothelial cells
endothelial cells produce what? (thin; forms the outer surface of capillary)
basal lamina
penetrate the capillary wall; water-filled; go between endothelial cells
intercellular clefts
what can cross freely through the capillary wall?
O2 CO2 and water
can proteins and plasma proteins cross the capillary wall?
proteins and restricted; plasma proteins cannot
capillaries within what organ are very permeable?
liver
capillaries within what organ are impermeable?
brain
fluid movement across capillary walls is driven by
starling forces
create pressure differences across capillary wall, fluid flows from high to low pressure
starling forces
movement down a pressure gradient
bulk flow
movement of fluid from plasma to ISF
filtration
movement of fluid from ISF to plasma
absorption
what are the two starling forces?
hydrostatic and osmotic pressure
pressure exerted by a fluid on the capillary wall; push force
hydrostatic pressure (P)
push fluid from plasma to ISF, promoting filtration
plasma hydrostatic pressure (Pc)
push fluid from ISF to plasma, promoting absorption
ISF hydrostatic pressure (Pi)
pressure that draws water from one compartment to another, pull force
osmotic pressure
pressure that pulls fluid from ISF to plasma, promoting absorption
plasma osmotic pressure
pulls fluid from plasma to ISF, promoting filtration
ISF osmotic pressure
2 forces that promote absorption (hydro press of ISF and osmo press of plasma)
absorption pressure