Hemodynamics Flashcards

1
Q

What is vasculature?

A

the blood vessels of the body

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2
Q

What is a circuit?

A

a network of blood vessels that begins and ends at the heart

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3
Q

what circuits are the vasculature divided into?

A

pulmonary and systemic circuit

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4
Q

What does the pulmonary circuit contain?

A

the blood vessels within the lungs, and those that transport blood bw the heart and lungs

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5
Q

what does the systemic circuit contain?

A

blood vessels within all other organs, and those that transport blood between the heart and those organs

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6
Q

What is series flow?

A

the movement of blood thru different types of blood vessels in sequence

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7
Q

what are the 5 types of blood vessels?

A

arteries, arterioles, capillaries, venules, veins

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8
Q

what is parallel flow?

A

movement of blood thru different organs at the same time

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9
Q

What is blood flow?

A

the rate at which blood moves thru the vasculature

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10
Q

what does blood flow measure?

A

the efficiency of blood movement to and from the tissues

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11
Q

what are the determinants of blood flow?

A

pressure difference and vascular resistance

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12
Q

What is pressure difference?

A

the force that drives blood thru the circuits

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13
Q

What ventricle drives the blood thru the pulmonary circuit?

A

right ventricle

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14
Q

What ventricle drives the blood through the systemic circuit?

A

left ventricle

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15
Q

what are the units of pressure difference?

A

mmHg or kPa

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16
Q

what does pressure difference calculation rely on?

A

mean arterial pressure (MAP)

17
Q

how does blood pressure vary during the cardiac cycle?

A

high during systole, low during diastole

18
Q

does the pressure difference vary between circuits? How so?

A

yes, pulmonary circuit is usually 15mmHg and 95 mmHg in the systemic circuit

19
Q

what is vascular resistance?

A

an impediment to blood flow; a measure of how much friction is encountered by blood as it moves thru the vasculature

20
Q

what are the 3 determinants of resistance in a single blood vessel?

A

length, radius of blood vessel, viscosity of blood

21
Q

what is blood viscosity affected by? what is it and what is its relationship with viscosity?

A

hematocrit; the percent of blood vol occupied by red blood cells; as hematocrit increases so does viscosity

22
Q

what factors increase resistance? decrease resistance?

A

increases with increasing length and viscosity; decreases with increasing radius

23
Q

what causes blood flow to increase and decrease?

A

increases with increased pressure difference and radius; decreased with increasing length and viscosity

24
Q

changes in radius have what kind of effect on flow? what does that mean?

A

disproportionate; small changes in radius will have a large effect on flow

25
what is total peripheral resistance (TPR) and systemic vascular resistance (SVR)?
resistance in the systemic circuit
26
what is pulmonary vascular resistance (PVR)?
resistance in the pulmonary circuit
27
what is a typical TPR?
19 mmHg/L/min
28
what is a typical PVR?
3 mmHg/L/min
29
Why is PVR lower than TPR?
the pulmonary circuit is shorter, and arterioles are structured different from those in the systemic circuit
30
what is the main source of resistance in the systemic circuit? what percentage?
resistance within the arterioles; 60%
31
what happens to arterioles when the smooth muscle within it contracts?
decreases arteriole radius and increases resistance
32
what happens to arterioles when the smooth muscle within it relaxes?
increase arteriole radius and decrease resistance