MICROBIOLOGY- Systems Flashcards
Most common bacteria found in the skin
S. epidermidis
These bacterias are commonly found in Nose
S. epidermidis, colonized by S. aureus
This bacteria is the most common in oropharynx
Viridians group streptococci
Normal flora in dental plaque
S. mutans
Who are the most common bacterias found in Colon?
Bacteriodes fragilis > E. coli
Name the most common bacterias in vagina
Lactobacillus, colonized by E. coli and group B strep
Which patients have no flora?
Neonates delivered by C-section, but are rapidly colonized after birth
These bacterias cause a food poisoning that starts quickly and ends quickly
S. aureus and Bacilus cereus
Which food poisoning is related to Bacilus cereus?
Reheated rice
This bacteria caused food poisoning and is seen in improperly canned foods
C. botulinum
In which food can we see C. perfringens?
Reheated meat dishes
This bacteria is commonly found in undercooked meat
E. coli O157: H7
Which foods can cause Salmonella infection?
Poultry, meat and eggs
Which food S. aureus commonly contaminates?
Meats, mayonnaise, custard
In S. aureues structure, what is the cause of food poisoning?
Preformed toxin
These bacterias cause food poisoning by contamined seafood
V. parahaemolyticus and V. vulnificus
This bacteria is acquired by wound infection from contact with contamined water or shellfish
V. vulnificus
Name the commonly bugs causing bloody diarrhea
Campylobacter E. histolytica Enterohemorrhagic E. coli Enteroinvasive E. coli Salmonella Shigella Y. enterocolitica
These microorganisms cause watery diarrhea
C. difficile C. perfringens Enterotoxigenic E. coli Protozoa V. cholerae Viruses (Rotavirus, norovirus)
In neonates < 4 wk which are the common pathogens causing pneumonia?
Group B streptococci
E. coli
In children 4 wk-18 YR which are the common pathogens causing pneumonia?
Viruses (Respiratory Syncytal Virus) Mycoplasma C. trachomatis C, pneumoniae S. pneumoniae
Who are more common affected by C. trachomatis causing pneumonia?
Infants 3 yr
Which pathogen is the most common in school aged children causing pneumonia?
C. pneumoniae
For adults (18-40 YR) these are the most common microorganisms that cause pneumonia
Mycoplasma
C. pneumoniae
S. pneumoniae
Who are the most common pathogens that cause pneumonia in adults (40-65 YR)?
S. pneumoniae H. influenzae Anaerobes Viruses Mycoplasma
In eldery these are the most common microorganisms that cause pneumonia
S. pneumoniae Influenza Virus Anaerobes H. influenzae Gram negative rods
For alcoholic/ IV drug user these are the most common pathogen causing Pneumonia
S. pneumoniae, Klebsiella, Staphylococcus
If aspirated these are the common microorganism that cause pneumonia
Anaerobes
Consider the microorganisms that cause atypical pneumonia
Mycoplasma
Legionella
Chlamydia
In cystic fibrosis, who are the main pathogens causing pneumonia?
Pseudomonas
S. aureus
S. pneumoniae
For immninocopromised, these are the main microorganisms that cause pneumonia
Staphylococcus Enteric gram negative rods Fungi Viruses P. jirovecii (HIV)
These are the most common pathogen hospital acquired (nosocomial)
Staphylococcus
Pseudomonas
Other Enteric gram negative rods
Postviral infection this are the most common bacterias causing pneumonia
Sthapylococcus
H. influenzar
S. pneumoniae
Which are the most common causes of meningitisin new born (0-6 MO)?
Group B streptococci
E. Coli
Listeria
For children (6 MO- 6 YR), these are the most common microorganisms that cause meningitis
S. Penumoniae
N meningitidis
H. influenzae type B
Enteroviruses
In patients from6-60 YR, who are the most common pathogen that cause Meningitis?
S. pneumoniae
N. meningitidis
Enteroviruses
HSV
Which is the number one microorganism that causes Meningitis in teens?
N. Meningitidis
For people older than 60 YR, these are the most common microorganisms that cause Meningitis
S. pneumoniae
Grma negative rods
Listeria
If you suspect a case of meningitis, which medicines are given empirically?
Ceftriaxone and vancomycin
If you suspect a case of Listeria causing meningitis, which is the treatment?
Cefriaxone and vancomycin add ampicillin
Which are the viruses that can cause meningitis?
Enteroviruses (coxsackievirus) HSV-2 HIV West Nile virus VZV
Which is the reason H. influenzae meningitis has decreased?
Because of the introduction if conjugate H. influenzae vaccine in last 10-15 years
In whom is more common to see H. influenzae meingitis?
Unimmunized children
Which are the parameters searched in Cerebrospinal fluid?
Opening pressure
Cell type
Protein
Sugar
If looking for meningitis caused by bacterias which are the expected results in CSF?
↑ Opening pressure
↑ PMN
↑ Proteins
↓ Sugar
In case of meningitis caused by fungal/TB which are the expected results in CSF?
↑ Opening pressure
↑ lymphocytes
↑ Proteins
↓ Sugar
If you suspect of meningitis caused by virus, which are the expected results in CSF?
↑/ Normal Opening pressure
↑ lymphocytes
↑/ Normal Proteins
Normal Sugar
You must assume if no other information is available that this bacteria is the cause of osteomyelitis
S. aureus (most common overall)
Which are the risk factor for Osteomyelitis?
Sexually active Diabetics and IV drug users Sickle cell Prosthetic joint replacement Vertebral involvement Cant and dog bites
This bacteria is a rare cause of ostemyelitits if the patient is sexually active
Neisseria fonorrhoeae, septic arthitis more common
Which bacterias are found in diabetics and IV drug users in osteomyelitis patients?
Pseudomona aeruginosa
Serratia
For sickle cell patients this bacteria is related to osteomyelitis
Salmonella
After a prosthetic joint replacement, you must suspect these bacterias in case of osteomyelitis
S. aureus and S. epidermidis
If you see osteomyelitis with vertebral involvement, you must suspect…
Mycobacterium tuberculosis
What is the name of the disease caused by mycobacterium that involves osteomyelitis?
Pott disease
This is the recognize bacteria found in osteomyelitis in case of cat and dog bites
Pateurella multocida
Which group of age is the most common affected by osteomyelitis?
Children
These nonspecific lab test work for osteomyelitis
CRP
ESR
Which imaging studies help in the diagnosis of osetomyelitis?
Subtle in radiographs
More easily seen on MRI
Which are the findings in patients with cystitis?
Dysuria, frequency, urgencym suprapubic pain, and WBCs in urine
Which is the primarily mechanism of acquiring cystitis?
Ascension of microbes fro urethra to bladder
In male infants these are reasons of urinary tract infections
Congenital defects
Vesicoureteral reflux
In eldery men this is the main reason of Urinary tract infection
Enlarged prostate
Which could be the problem if an urinary tract ascends to the kidneys? Which could be the findings in this disease?
Pyelonephritis
Fever, chillsm flank pain costovertebral angle tenderness, hematurua and WBC casts
Who are at higher risk for urinary tract infections?
Ten times more common in women
This is the main reason why is more comon urinary tract infections in women than in men
Shorter urethras colonized by fecal flora
Name other predisposing factor that lead to UTI
Obstruction, kidney surgery, catheterization, GU malformation, diabetes and pregnancy
Which are the diagnostic markers for Urinary tract infection?
Leukocyte esterase test +
Nitrite test +
What does the leujocyte esterase test + indicates?
Bacterial UTI
If nitrite test is positive, what does it means?
Gram negative bacterial UTI
In case of urease tests in urine is positive, what do you suspect?
Urease producing bugs (Proteus, klebsiella)
If urease test in urine is negative and you have a UTI, which bacterias are the cause?
E. coli, Enterococcus
Which bacteria is the leading cause of UTI?
Escherichia Coli
Which culture is used for E. Coli?
EMB agar
What does the E. Coli agar shows in the EMB agar?
green metalic sheen
Consider the 2nd leading cause of UTI
Staphylococcus saprophyticus
In which patients is more common to see staphylococcus saprophyticus?
Sexually active women
This bacteria is the third leadin cause of UTI
Klebsiella pneumoniae
Which are characteristics of Klebsiella pneumoniae?
Large mucoid capsule and viscous colonies
These three UTI bacterias are acquired nosocomialy and are drug resistant
Serratia marcescens
Enterobacter cloacae
PSeudomona aeruginosa
Some strains of this UTI bacteria produce a red pigment
Serratia marcescens
Which UTI bacteria produces swarming on agar?
Proteus mirabilis
Why does Proteus mirabilis produces swarming on agar?
Because of its Motility
This UTI bacteria is associated with struvite stones
Proteus mirabilis
Which UTI bacteria produces blue green pigment and fruit odor?
Pseudomonas aeruginosa
Who causes the most common vaginal infections?
Bacterial vaginosis
Trichomoniasis
Candida vulvovaginitis
This vaginal infection curse with no inflamation, thin, white discharge with fishy odor
Bacterial vaginosis
Which are the lab findings in Bacterial vaginosis?
Clue cells
pH >4.5
Which is the selected treatment for Bacterial vaginosis?
Metronidazole
Which are the characteristics of Trichomoniasis in vaginal infection?
Inflammation
Frothy, grey green
Foul smeelling discharge
Which characteristics are found in Lab test for trichomoniasis?
Motile thrichomonads
pH >4.5
In case of vaginal infection by Trichomoniasis, which is the recomended treatment?
Metronidazole
Treat sexual partner
These are the characteristics of Candida vulvovaginitis
Inflammation
Thick, white, cottage cheese discharge
What is found in lab studies in case of candida vulvovaginitis?
Pseudohyphae pH normal (4.0-4.5)
For Candida vulvovaginitis this is the recomended treatment
Azoles
Who are the agents that cause ToRCHeS infections?
Toxoplasma gondii Rubella CMV HIV Herpes simplex virus-2 Syphillis
How is acquired ToRCHeS infection?
Microbes that may pass from mother to fetus
Which are the modes of transmission of ToRCHeS infections?
Transplacental in most cases or via delivery (especially HSV-2)
Which are non specific signs of ToRCHeS infections?
Hepatosplenomegaly, jaundice, thrombocytopenia, and growth retardation
These are other important infectious agents not included in ToRCHeS
Streptococcus agalactie (group B streptococci)
E. coli
Listeria monocytogenes
What can Streptococcus agalactie (group B streptococci), E. coli, Listeria monocytogenes cause in the neonate?
Meningitis
Virus that causes Hydrops fetalis
Parvovirus B19
Mode of transmission of Toxoplama gondii
Cat feces or ingestion of undercooked meat
How is Toxoplasma gondii infection maternal manifested?
Usually asymptomatic lymphadenopathy (rarely)
This is the classic triad of Toxoplasma gondi in neonates
Chorioretinitis
Hydrocephalus
Intracranial calcifications
This is the maternal manifestaion of Rubella
Rash, lymphadenopathy, arthritis
How is transmitted Rubella?
Respiratory droplets
In neonates this is the classic triad of Rubella
Patent ductus arteriosus (PDA) or pulmonary artery hypoplasia
Cataracts
Deafness
Which sign can be or not present in Rubella patients?
Blueberry Muffin rash
Which could be the presentation of HIV in maternal patients?
Variable depending on CD4+ count
Which are the ways of transmission of HIV?
Sexual contact, needle stick
How is HIV manifested in neonates patients?
Recurrent infections, chronic diarrhea
In mothers how is manifested Herpes simple virus-2 in mothers?
Usally asymptomatic
Herpetic vesicular lesions
How is hepres simple virus-2 transmitted?
Skin or mucous membrane contacr
These are the manifestations in neonanets that adquired Herpes simple virus-2
Encephalitis
Herpetic vesicular lessions
How is syphilis acquired?
Sexual contact
Which are the two stages of syphilis that can result in fetal infecion?
Chancre (1º) Disseminated rash (2º)
Which are the common results of syphillis in neonates?
Stillbirth
Hydrops fetalis
Which could be the results of Syphillis in neonates that survive?
Facial abnormalities:
Notched teeth, Saddle nose, short maxilla
Saber shins
CN VIII deafness
These microorganisms can cause red rashes of childhood
Coxsackievirus type A HHV-6 Measles virus Parvovirus B19 Rubella virus Streptococcus pyogenes VZV
This virus causes Hand-Foot-mouth disease
Coxsackievirus type A
How is Hand-Foot-mouth disease manifested?
Vesicular rash on plams and soles
Vesicles and ulcers in oral mucosa
Which red rash of childhood can HHV-6 cause?
Roseola
Which are the clinical manifestations of Roseola?
A macular rash over body appear after several days of high fever; can present with febrile seizures; ussually affects infants
Paramyxovirus that causes red rash of childhood
Measles virus
How is the clinical evolution of Measles?
Rash Beginning at head and moving down
Which are the findings that precede the rash in measles
Cough, coryza, conjunctivitis, and blue white (Koplik) spots on buccal mucosa
Who causes Erythema infectiosum (fifth disease)?
Parvovirus B19
Which is the clinical manifestation of Parvovirus B19 of Fifth disease?
Slapped cheek rach on face
What other presentation can Parvovirus B19 has?
Hydrops fetalis in pregnant women
Which is the progression of Rubella rash? and which other clinical presentations does it has?
Rash begins at head and moves down → Fine truncal rash
Postauricular lymphadenopathy
Which rash can Streptococcus pyogenes cause in childhood?
Scarlet fever
Which is the clinical presentation of Scarlet fever?
Erythematous, sandpaper-like rash with fever and sore throat
How causes chikenpox?
VZV
This is the presentation of Chikenpox
Vesicular rash begins in trunk
Spreads to face and extremities with lesions of different ages
Consider sexually transmitted diseases
AIDS Chancroid Chlamydia Condylomata acuminara Genital herpes Gonorrhea Hepatitis B Lymphogranuloma venerum 1º, 2º and 3º syphilis Trichomoniasis
How is AIDS manifested?
Oportunitic infections
Kaposi sarcoma
Lymphoma
Painful genital ulcer characterized by inguinal adenopathy
Chancroid
Who causes Chancroid?
Haemophilus ducreyi
Which types of Chlamydia are Trachomatis?
D-K
These could be the clinical manifestations of Chlamydia
Urethritis, cervicitis, conjuntivits, reactive arthritis, PID
Which disease is characterized by Genital warts?
Condylomata acuminata
Which squamos epithelial cells are from Condylomata acuminata?
Koilocytes
Which viruses cause Genital warts?
HPV-6 and 11
How is Genital herpes manifested?
Painful penile, vulvar or cervical vesicles and ulcers
Which other symptoms can Genital herpes cause?
Fever, headache, myalgia
Who causes Genital herpes?
HSV-2, less common HSV-1
These could be the clinical features of Neisseria Gonorrhoeae infection
Urethritis, cervicitis, PID, prostatitis, epydidymitis, arthritis, creamy purulent discharge
Which is the clinical manifestation of Hepatitis B
Jaundice
Who causes Lymphogranuloma venerum?
C. trachomatis (L1-L3)
How is Lymphogranuloma venerum manifested?
Infection of lymphatics; painless genital ulcers, painful lymphadenopathy (buboes)
Who causes painles chancre?
1º syphilis
This bacteria is responsable for 1º, 2º and 3º syphilis
Treponema pallidum
Which are the clinical features of 2º syphilis?
Fever, lymphadenopathy, skin rashes, condylomata lata
These are the findings in 3º syphilis
Gummasm tables dorsalis, general paresis, aortitis, Argyll Robertson pupil
What can Trichomana vaginalis cause?
Vaginitis, strawberry cervix, motile in wet prep
Which is the most common sexual transmitted disease in USA?
Pelvic inflamatory disease
Which are the principal bugs that cause Pelvic inflamatory disease?
Chlamydia Trachomatis
Neisseria gonorrhoeae
Often undiagnosed, subacute cause of Pelvic inflamatory disease
Chlamydia trachomatis
Acute cause of Pelvic inflamatory disease
Neisseria gonorrhoeae
Which are the common findings in Pelvic inflamatory disease?
Cervical motion tenderness
Purulent cervical discharge
What is the name for cervical motion tenderness?
Chandelier sign
Which could be the complications of Pelvic inflamatory disease?
Slapingitis
Endometritis
Hydrosapinx
Tubo’ ovarian abscess
What can Pelvic inflamatory disease can lead related to the liver?
Fitz Hugh Curtis syndrome
What is Fitz Hugh Curtis syndrome?
Infection of the liver capsule and violin string adhesions of peritoneum to liver
Risk factor for ectopic pregnancy, infertility, chronic pelvic pain, and adhesions
Salpingitis
Which are the most common microorganisms that cause Nosocomial infections?
Candida albicans CMV, RSV E. coli, Proteus mirabilis HBV Legionella Pseudomona aeruginosa
This nosocomial bacteria can be acquired by hyperalimentation
Candida albicans
Which viruses can be acquired in newborn nursery?
CMV
RSV
Which bacterias are aquired by urinary catheterization?
E. coli
Proteus mirabilis
Who are the most common causes of nosocomial infections?
E. coli (UTI) and S. aureus (wound infection)
This microorganism can be acquired during work in renal dialysis unit
HBV
Which nosocomial microoganism is aquired by water aerosols?
Legionella
Which bacteria you should thinl when water spurce is involved?
Legionella
Nosocomially how can you acquired Pseudomona aeruginosa infection?
Respiratory therapy equipment
When you should think of pseudomona aeruginosa infection?
When air or burns are involved
In unimmunized children this could be the posible presentations
Dermatologic
Neurologic
Respiratory
This microorganism is represented by a rash that beggins at head and moving down with posauricular lymphadenopathy
Rubella virus
This microorganism is represented by a rash that beggins at head and moving down, preceded by cough, coryza, conjuntivitism and Koplik spots on buccal mucosa
Measles virus
Which pathogens can be present that cause rash in unimmunized children?
Ribella virus
Measles virus
Which microorganism can cause meningitis in unimmunized children?
H. influenzae type B
Poliovirus
This microbe colonizes nasopharynx and in unimmunized children can cause meningitis
H. influenzae type B
What else can Poliovirus cause in unimmunized children?
Lead to myalgia and paralysis
This is the most common reason of Epiglottitis
H. influenzae type B
How is characterized Epiglottitis?
Fever with dysphagia, drooling and difficulty breathing due to edematous “Cherry red” epligottis
Which is the famous sign found on X ray in case of Epiglottitis?
Thumbprint sign
Which microorganism causes Pharyngitis in unimmunized children?
Corynebacterium diphteriae
Which are the clinical findings in pharyngitis from Corynebacterium diphteriae?
Grayish oropharyngeal exudate (pseudomembranes may obstruct airway)
Painful throat
These microorganisms affect principally asplenic patients
Encapsulated microbes
Who are consider encapsulated microorganism?
S.pneumoniae» H. Influenzae type b> N. Meningitidis
Branching rods in oral infections, sulfur granules
Actinomyces israeli
These type of mycrobes can cause chronic granulamatous disease
Catalase + microbes, especially S. Aureus
Currant jelly sputum
Klebsiella
Obtain by cat or dog bite
Pasteurella multocida
This bacteria can cause Facial nerve palsy
Borrelia burgdorferi
This disease is caused by Borrelia burgdorferi
Lyme disease
Fungal infection in diabetic or immunocompromised patients
Mucor or Rhizopus spp
This microorganism can be acquired in health care providers from needle sticks
HBV
These pathogens are the most common to affect neutropenic patients
Candida albicans (systemic) Aspergillus
This microorganism is common in organ transplant recipient
CMV
Who causes whipple disease?
Tropheryma whipplei
Which stain is useful for Tropheryma whipplei?
PAS +
Most common source of pediatric infection
Haemophilus influenzae
This is the most common cause of epiglottitis
H. Influenzae
Causes pneumonia in cystic fibrosis
Pseudomona aeruginosa
Most common microorganism in burn infection
Pseudomona aeruginosa
This bacteria appears with pus, empyema and abscess
S. Aureus
Which microorganisms can cause rash on hands and feet?
Coxsackie A virus
Treponema pallidum
Rickettsia ricketssi
Most common cause of sepsis/ meningitis in newborn
Group B strep
Most common pathogen in surgical wounds
S. Aureus
Which is the most common microoganism present in traumatic open wound?
Clostridium perfringens