Microbiology of skin infections Flashcards
What are the skin’s defences against infection?
Intact skin is much less likely to become infected
Dry - dessication of microorganisms
Sebum - fatty acids inhibit bacterial growth
Competitive bacterial flora
Concept of resident and transient flora
What are common competitive bacterial flora on the skin?
Staphylococcus epidermis
Corynebacterium (diptheroids)
Propionibacterium
How are bacterial skin infections diagnosed?
Swab of lesions if surface broken
Pus or tissue if deeper lesion
+/- blood cultures if appropriate
How will staph auerus coagulase?
Golden
Positive coagulase
What are the different species of alpha haemolytic streptococcus chains?
Step pneumoniae
Strep viridans
What are the different species of beta haemolytic streptococcus chains?
Group A strep (throat, skin infection)
Group B strep (neonatal meningitis)
Group C, G strep
What are the different species of non haemolytic streptococcus chains?
Enterococcus (gut commensal, UTI)
What are the different species of coagulase positive staphylococcus clusters?
Staph aureus (wound, skin infection)
What are the different species of coagulase negative staphylococcus clusters?
Staph epidermis
In what air conditions will staphylococcus grow?
Aerobic and facultatively anaerobic
What are some virulence factors that staphylococcus aureus can produce?
Enterotoxin - food poisining
SSSST - staphylococcal scalded skin syndrome toxin
PVL - panton valentine leucocidin
What bacterial skin infections can staph aureus cause?
Boils and carbuncles Infected cuts Cellulitis Infected eczema Impetigo Wound infection Staphylococcal scalded skin syndrome
What are the treatment options for MRSA?
Skin or soft tissue - doxycycline, co-trimoxazole, clindamycin
Blood stream - vancomycin
What infections are staphylococcus epidermis bacteria associated with?
Implanted artifical material such as artifical joints, artifical heart valves, IV catheters
In what air conditions will streptococcus species grow?
Aerobic and faculatively anaerobic