Microbiology - NBS Flashcards
Neurtophils, monocytes and macrophages are all examples of ________
Phagocytes
________, ________ and ________ are all immune cells that release inflammatory mediators
Basophils, Mast Cells, Eosinophils
________ start as a monocyte and present antigens to T Cells
Macrophages
________ poduce cytokines, can activate helper and cytotoxic T cells and kill pathogen or tumor cells
Macrophages
________ ________ cells can inactivate pathogens
Natural Killer
Macrophages are considered part of our ________ Immune System
Innate
Killer-/Helper-/Regulatory-T Cells are all part of our ________ Immune System
Adaptive
The 3 main types of T cells are ________, ________ and ________
Helper T Cells
Killer T Cells
Regulatory T Cells
________ kill virus-infected cells with/without antibody by triggering target cell to “commit suicide”
Killer T Cells
________ help in antigen recognition and regulation, secrete cytokines (Interleukin 2 and Interferon Gamma), and activate helper and killer T cells and kill pathogen or tumor cell
Helper T Cells
________ help other T cells keep “under control”
Regulatory T Cells
Match the correct Type hypersensitivity reaction with its relative brief description
Type———————————-Description
I—————————————–Antibody mediated
II—————————————-T Cell mediated
III—————————————Immediate hypersensitivity
IV————————————–Immune complex mediated
Type———————————-Description
I—————————————–Immediate hypersensitivity
II—————————————-Antibody mediated
III—————————————Immune complex mediated
IV————————————–T Cell mediated
Remember the acronym "I AM IT" I = "I" II = "AM" III = "I" IV = "T"
Type ________ hypersensitivity is associated with IgE, mast cells, basophils, allergic mediators and anaphylaxis, hay fever and asthma
a. I
b. II
c. III
d. IV
a. I
Type ________ hypersensitivity is associated with IgG, IgM, cause cell lysis and blood group incompatibility, pernicious anemia and myasthenia gravis
a. I
b. II
c. III
d. IV
b. II
Type ________ hypersensitivity is associated with IgG, antibody-mediated inflammation and SLE, RA, serum sickness and rheumatic fever
a. I
b. II
c. III
d. IV
c. III
Type ________ hypersensitivity is delayed and associated with infections, dermatitis, graft rejections, poison oak, and poison ivy
a. I
b. II
c. III
d. IV
d. IV
Match the WHO report with the appropriate year
WHO Report——————————————-Year
SARS out break in China————————–2013
Avian flu outbreak Asia—————————-2012
Hantavirus in Yosemite State Park————2003
Meningitis + West Nile virus———————-2002
Pertusis————————————————–
Norovirus————————————————
Salmonella———————————————-
8.8 million new cases of TB———————-
1.4 million deaths from TB————————
WHO Report——————————————-Year
SARS out break in China————————–2002
Avian flu outbreak Asia—————————-2003
Hantavirus in Yosemite State Park————2012
Meningitis + West Nile virus———————-2012
Pertusis————————————————–2012
Norovirus————————————————2013
Salmonella———————————————-2013
8.8 million new cases of TB———————-2013
1.4 million deaths from TB————————2013
________ is where self-reactive lymphocytes are repeatedly stimulated and the result is swollen lymph nodes
a. Insulin-dependent diabetes mellitus
b. Canale-Smith Syndrome
c. Multiple sclerosis
d. Myasthenia gravis
b. Canale-Smith Syndrome
________ is where self-reactive antibodies bind to receptors for acetylcholine
a. Insulin-dependent diabetes mellitus
b. Canale-Smith Syndrome
c. Multiple sclerosis
d. Myasthenia gravis
d. Myasthenia gravis
________ is where self-reactive T cells destroy myelin sheaths
a. Insulin-dependent diabetes mellitus
b. Canale-Smith Syndrome
c. Multiple sclerosis
d. Myasthenia gravis
c. Multiple sclerosis
________ is a chronic inflammation of joints involving IgM-IgG activation of macrophages
a. Rheumatoid arthritis
b. Lupus erythematosus
c. Multiple sclerosis
d. DiGeorge Syndrome
a. Rheumatoid arthritis
________ can cause inflammation of the lungs, arthritis, kidney damage, hair loss, paralysis and convulsions and is caused by the breakdown of B and T cells that make IgG antibodies
a. Rheumatoid arthritis
b. Lupus erythematosus
c. Multiple sclerosis
d. DiGeorge Syndrome
b. Lupus erythematosus
________ can occur when the thymic tissue is missing, leading to no T cells, making the patient susceptible to life-threatening infections
a. Rheumatoid arthritis
b. Lupus erythematosus
c. Multiple sclerosis
d. DiGeorge Syndrome
d. DiGeorge Syndrome
________ is where there are no T or B cells
a. AIDS
b. Severe Combined Immunodeficiency Syndrome
c. Multiple sclerosis
d. DiGeorge Syndrome
b. Severe Combined Immunodeficiency Syndrome
________ is where helper T cells are targeted. Patient is susceptible to Pneumocystis carinii
a. AIDS
b. Severe Combined Immunodeficiency Syndrome
c. Multiple sclerosis
d. DiGeorge Syndrome
a. AIDS
Match the following immunities to the detail
Detail———————————————–Immunity
Live (attenuated) or killed viruses——–Passive-active
Mother’s milk————————————Active
Immune globulins + vaccine—————Passive
Detail———————————————–Immunity
Live (attenuated) or killed viruses——–Active
Mother’s milk————————————Passive
Immune globulins + vaccine—————Passive-active
Which type of vaccine is designed not to infect the recipient?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
d. Noninfectious vaccines
Which type of vaccine is Salk an example of?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
d. Noninfectious vaccines
Which type of vaccine is using a weakened form of a microbe an example of?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
a. Attenuated vaccines
Which type of vaccine are most vaccines an example of?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
a. Attenuated vaccines
Which type of vaccine is genetically engineered?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
b. Carrier vaccines
Which type of vaccine is where a single gene from a pathogenic microbe is introduced into a virus and does not cause disease (called a “Trojan horse”)?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
b. Carrier vaccines
Which type of vaccine is where a piece of DNA which has the flu virus gene is injected?
a. Attenuated vaccines
b. Carrier vaccines
c. DNA vaccines
d. Noninfectious vaccines
c. DNA vaccines
Infections, dermatitis and graft rejections are examples of Type ________ hypersensitivity reactions
IV
SLE and RA are examples of Type ________ hypersensitivity reactions
III
Match the following acid-fast staining details to their appropriate counterpart
Detail———————————————-Counterpart
Crystal Violet———————————–Mordant
Alcohol rinse———————————–Counterstain
Gram’s iodine———————————-Purple
Safranin——————————————Red
Gram (+)——————————————Primary dye
Gram (-)——————————————-Decolorizer
Detail———————————————-Counterpart
Crystal Violet———————————–Primary dye
Alcohol rinse———————————–Decolorizer
Gram’s iodine———————————-Mordant
Safranin——————————————Counterstain
Gram (+)——————————————Purple
Gram (-)——————————————-Red
ELISAs and Western Blot tests are used to test for
a. MLS
b. ALS
c. MS
d. HIV
d. HIV
________ presents antigen to T cell
Marophages
Anaphylaxis is an example of a Type ________ hypersensitivity reaction
I
SLE and RA are both examples of Type ________ hypersensitivity reactions
III
Infections and dermatitis are both examples of Type ________ hypersensitivity reactions
IV
________ inactivate pathogens
Natrual Killer Cells
An ________ is the part of the antigen recognized by the immune system
Epitope
The following agency/organization performs epidemiological studies
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
b. Center for Disease Control
The following agency/organization performs research in disease etiology/prevention
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
b. Center for Disease Control
The following agency/organization performs sets recommendations for immunization schedules
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
b. Center for Disease Control
The following agency/organization works with public health organizations of other countries
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
b. Center for Disease Control
The following agency/organization coordinates efforts to improve public health in the world
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
e. World Health Organization
The following agency/organization reviews reports of public health assessment before information is disclosed to the public
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
a. Agency for Toxic Substance and Disease Registry
The following agency/organization is a special US EPA list of national hazardous waste sites
a. Agency for Toxic Substance and Disease Registry
b. Center for Disease Control
c. Nationally Priorities List
d. U.S. Public Health Service
e. World Health Organization
c. Nationally Priorities List
The following department is in charge of chiropractic (and other health modalities) licensure and other health related issues, infected meat, food products recalled
a. Department of Environmental Protection
b. Department of Health
c. Public Health Department
b. Department of Health
The following department is in charge of protecting air, water and land
a. Department of Environmental Protection
b. Department of Health
c. Public Health Department
a. Department of Environmental Protection
The following department is in charge of servicing healthneeds, especially underprivileged
a. Department of Environmental Protection
b. Department of Health
c. Public Health Department
c. Public Health Department
________ is treated polio virus with formaldehyde to kill the virus
Salk
________ uses live and attenuated virus for this vaccine
Sabin
Match the following bacteria type with the appropriate adjective
Type—————————————-Adjective
Bacilli—————————————Spherical
Cocci—————————————Rod-shaped
Spirochete——————————-Spring
Spirilla————————————-Spiral
Type—————————————-Adjective
Bacilli—————————————Rod-shaped
Cocci—————————————Spherical
Spirochete——————————-Spiral
Spirilla————————————-Spring
Match
Living Situation———-Definition
Symbiosis—————–one benefits, other doesn’t care
Mutualism—————–one benefits, other eaten
Parasite——————–both benefit
Commensalism———2 live together ok
Living Situation———-Definition
Symbiosis—————–2 live together ok
Mutualism—————–both benefit
Parasite——————–one benefits, other eaten
Commensalism———one benefits, other doesn’t care
________ can be found in custard filled pastry, egg, tuna fish salad and occurs 2-4 hours after infection
Staph
________ can be found in improperly canned veges and smoked fish and occurs 18-26 hours after infection
Botulism
________ can be found in unpasteurized milk products, hot dogs, lunch meats and occurs up to 2 weeks after infection
Listeria
________ can be found in undercooked meat, vegetables, fruit exposed to fecal material and occurs 2 days after infection
E. coli
________ can be found in poultry, meats and eggs and occurs 12-48 hours after infection
Salmonella
________ can be found in foods and water and occurs 1-2 days after infection
Shigella
________ can be found in seafood and water and occurs 1-5 days after infection
Cholera
________ can be found in undercooked meat and occurs 3 hours to 3 weeks after infection
Francisella tularensis
________ can be found in raw milk, is associated with TB and occurs months to years after infection
Mycobacterium bovis
In ________ there is sudden fever, severe headache, seizures, coma and approximately 50% die
a. Eastern Equine Encephalitis
b. Western Equine Encephalitis
c. West Nile
d. Yellow Fever
a. Eastern Equine Encephalitis
In ________ there is fever, headache, stiff neck, vomiting and approximately 3% die (mostly elderly + infants)
a. Eastern Equine Encephalitis
b. Western Equine Encephalitis
c. West Nile
d. Yellow Fever
b. Western Equine Encephalitis
In ________ there is fever, headache, abdominal pain and encephalitis
a. Rift Valley Fever
b. California Encephalitis
c. West Nile
d. Yellow Fever
b. California Encephalitis
In ________ there is bleeding and encephalitis
a. Rift Valley Fever
b. Dengue Fever
c. Colorado Tick Fever
d. Yellow Fever
a. Rift Valley Fever
________ occurred in Key West, FL in 2010 and is known to cause fever, rash, headache (known as dengue triangle)
a. Rift Valley Fever
b. Dengue Fever
c. Colorado Tick Fever
d. Yellow Fever
b. Dengue Fever
________ is known to cause fever, headache and nose bleeds
a. Rift Valley Fever
b. Dengue Fever
c. Colorado Tick Fever
d. Yellow Fever
d. Yellow Fever
________ is known to cause fever, headache, chills and eye pain
a. Rift Valley Fever
b. Dengue Fever
c. Colorado Tick Fever
d. Yellow Fever
c. Colorado Tick Fever
The following tick-spread disease causes fever, headache, chills and eye pain
a. Rocky Mountain Spotted Fever
b. Colorado Tick Fever
c. Lyme Disease
c. Colorado Tick Fever
The following tick-spread disease has a classic sign of a bulls eye rash and has been attributed to migraines and joint pain for the rest of a person’s life
a. Rocky Mountain Spotted Fever
b. Colorado Tick Fever
c. Lyme Disease
c. Lyme Disease
The following tick-spread disease causes a rash on the hands and feet
a. Rocky Mountain Spotted Fever
b. Colorado Tick Fever
c. Lyme Disease
a. Rocky Mountain Spotted Fever
________, ________, ________ and ________ are all considered re-emerging diseases
TB, Small Pox, Malaria and Mumps
________ is a rabies-like virus that leads to death
Lyssa virus
________ (aka Tsutsugamushi fever) causes a maculopapular rash
Scrub Typhus
________ is a fatal disease carried by pigs and bats that can lead to encephalitis and respiratory issues
Nipah Fever
________, also known as H5N1, or bird flu, leads to flu-like symptoms and can lead to complications and death
Avian Influenza
________ comes from a mosquito bite and can lead to encephalitis, high fever, and death
a. Lyssa virus
b. Nipah Fever
c. Chandipura virus
d. Norovirus
c. Chandipura virus
________ (aka Norwalk virus) is common in salad, sandwiches, ice, cold cuts, raw/undercooked oysters and clams, has a 1-2 day incubation period, and is estimated to cause 2/3 of all known foodborne illness in the US.
Norovirus
Which of the following is not gram positive
a. Staphylococcus aureus
b. Listeria monocytogene
c. Mycobacterium
d. Haemophilus
d. Haemophilus
Recall –> all bacteria that end in “US and UM” are gram positive except the one above