Microbiology Flashcards
1
Q
Early onset sepsis
A
Organisms: GBS (40%, most common), Ecoli (30%, highest mortality, mostly preterm)
- others: strep viridans, strep pneumo, staph aureus, enterococcus
Timing: onset <72 hours in NICU, or <7 days in term
- usually present within 6 hours
Transmission: vertical
RFs: low maternal GBS immunity, PROM > 18hr (1% risk), chorio (4%)
Tests: Total WCC poor PPV, BC (high conc in neonates), CRP triggered by IL-6 (rise within 6 hr and peak 24 hr) cut-off 10
Urine: not necessary as EOS UTI most likely secondary to renal seeding
LP: 38% meningitis negative BC
2
Q
Gram positive bacteria
A
3
Q
Gram negative bacteria
A