Microbiology Flashcards
Are listeria gram positive or gram negative?
Positive
Are bacillus sp. gram positive or gram negative?
Positive
Are Enterococcus sp. gram positive or gram negative?
Positive
Are the Staphylococci gram positive or gram negative?
Positive
Are the Streptococci gram positive or gram negative?
Positive
Are the Diptheroids gram positive or gram negative?
Positive
Are the Clostridium sp. gram positive or gram negative?
Positive
Is Klebsiella gram positive or gram negative?
Negative
Are the Proteus gram positive or gram negative?
Negative
Is Salmonella gram positive or gram negative?
Gram negative
Is Shigella gram positive or gram negative?
Negative
Are the helicobacter sp. gram positive or gram negative?
Negative
Is H. influenzae gram positive or gram negative?
Negative
Is legionella gram positive or gram negative?
Negative
Is E. coli gram positive or gram negative?
Negative
Is pseudomonas gram positive or gram negative?
Negative
Is camplylobacter gram positive or gram negative?
Negative
Is helicobacter gram positive or gram negative?
Negative
Is bacteroides gram positive or gram negative?
Negative
Are the diplococci gram positive or gram negative?
Negative
What are the diplococcal bacteria?
Meningitis and gonnorhoea
Is pertussis gram positive or gram negative?
Negative
What’s your mnemonic for the gram positive bacteria?
BLESS DC
What’s your mnemonic for the gram negative bacteria?
Katie probably had salmonella because she hardly played cards. Let everyone play dice.
What does it mean for an antibiotic to be bacteriostatic?
It doesn’t kill the pathogen, it just stops it growing. The white blood cells then kill it.
What are the macrolide antibiotics?
Clarythromycin
Azithromycin
Erythromycin
What’s the aminoglycoside antibiotic?
Gentamycin
How must gentamycin be given?
IM/IV
Is gentamycin good for gram positive or gram negative organisms?
Gram negatives
What antibiotic would you use for Pseudomonas aeruginosa?
Gentamycin IV
What antibiotic would you use for most hospital-acquired infections?
Gentamycin
What’s clindamycin used for?
Second-line in penicillin allergic patients, with Staph and Strep infections
What class of antibiotic would you use for intracellular infections?
Macrolides (azithroymcin, erythromycin,clarythromycin)
Which macrolide antibiotic can you give in pregnancy?
Erythromycin
What would you use for clostridium infection?
Erythromycin or clarithromycin
What antibiotic would you use for streptococcus infection??
Erithromycin or clarithromycin, or flucloxacillin
Which antibiotic would you use against staph. aureus?
Flucloxacillin
What antibiotic would you use against MRSA?
Gentamycin
What antibiotic would you use against Pseudomonas aeruginosa?
Gentamycin
What antibiotic would you use against E. coli?
Gentamycin
What antibiotic would you use against Neisseria spp.?
Gentamycin
What antibiotic would you use against an atypical pneumonia?
Doxycycline
Which antibiotic is used for Staphylococci and Streptococci only?
Flucloxacillin
What is flucloxacillin used for?
Staph and Strep
Which penicillin is good for gram positive organisms?
Flucloxacillin
What’s the antibiotic for C. diff infection?
Vancomycin oral
Name an antibiotic with really good gram positive cover.
Vancomycin
What are the side effects of gentamycin?
Damages kidneys
Deafness/dizziness
What are the side effects of vancomycin?
Red man syndrome
Kidney damage
What kind of hypersensitivity reaction is a true penicillin allergy?
Type 1
What are the 3 mechanisms by which bacteria gain resistance to antibiotics?
Tranformation
Conjugation
Transduction
What is bacterial transduction?
DNA transferred from one bacterium to antother by viruses - bacteriophages.
What is bacterial transformation?
Scavenging of free DNA from dead bacteria by other bacteria.
What is bacterial conjugation?
Transfer of plasmids by sex, using pili
Which antibiotics would you use for mild/moderate community-acquired pneumonia?
Amoxicillin
Which antibiotics would you use for mild/moderate community-acquired pneumonia? WITH PENICILLIN ALLERGY?
Doxycycline
What antibiotcs would you use for severe community-acquired pneumonia? (Remember the step-down too)
Co-amoxiclav with clarithromycin or doxycycline
Step down to doxycycline
What antibiotic would you give to someone with severe hospital-acquired pneumonia?
Amoxicillin, metronidazole, and gentamycin
What antibiotic would you give to someone with non-severe hospital-acquired pneumonia?
Amoxicillin and metronidazole
What antibiotic would you give for an acute exacerbation of COPD?
Amoxicillin
What’s the empirical therapy for endocarditis?
Gentamycin and vancomyin
What antibiotic would you give for non-severe C. diff infection?
Metronidazole
What antibiotic would you give for severe C. diff infection?
Vancomycin with or without metronidazole
What is the empirical antibiotic therapy?
Amoxicillin, metronidazole, gentamycin
What are the 4 C antibiotics?
Clindamycin
Cephalosporins
Co-amoxiclav
Ciprofloxacin
Why should you avoid the 4 C antibiotics?
Increase the risk of C. diff infection