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PNS > Microbiology > Flashcards

Microbiology Flashcards

1
Q

rabies morphology

A

bullet shaped, negative sense ssRNA
RNA dependent RNA polymerase E
coated

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2
Q

Boaintang causes:

A

rabies

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3
Q

stages of rabies

A
  1. incubation period : averages depending on the site of wound, asymptomatic , retrograde
  2. prodrome : 2-10 days with non specific symptoms and corresponds to invasion of dorsal root gang.
  3. neurological phase : 2-7 days , correspond to invsion of the CNS and might be encephalitic or initial paralytic
  4. coma : always death
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4
Q

encephalitic furious rabies symptoms

A

hypersalivation > ANS dysfunction
hydrophobia and aerophobia > contraction of throat and respiratory muscles
foaming mouth

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5
Q

most common sensitive technique for lab diagnosis of rabies is

A

PCR

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6
Q

Negri bodies are seen in

A

pyramidal cells and purkinje cells
positive. only when condition is almost fatal

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7
Q

rodent borne viruses are

A

arenaviridae
bunyaviridae (hentavirus)

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8
Q

arenaviride members and their conditions

A

lessa virus > lessa fever
machupo virus > bolivian hemorrhage fever
jeinin virus > argentine hemorrhage, fever
choriomeningitis v. > lymphatic choriomeningitis

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9
Q

bunyaviridae members and their dizs

A

hentavirus > hemorrhagic fever and renal syn.
sin nombre virus > hentavirus cardiopulmonary syn.

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10
Q

arboviruses families are:

A

togavirus
flavivirus
reovirus
bunyavirus

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11
Q

togavirus members, diz and vector

A

WEV, EEV, VEV > encephalitis
chickungunya v. , ross river fever > febrile

all caused by mosquitos

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12
Q

flavivirus, what members cause febrile , what members are carried by ticks

A

dengue, west, zika > febrile
powassan annd tick borne encephalitis virus > ticks

the rest are carried by mosquitoes and cause encephalitis

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13
Q

reovirus members and vector

A

colorado tick fever viruses and cause by ticks

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14
Q

bunyaviruses members and vectors
on arboviruses

A

rift valley , sand fly > febrile by sandfly
crimean congo > febrile by ticks
california > encephalitis by mosquitoes

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15
Q
  • arenaviruses and filoviruses that cause hemorrhagic fevers
  • bunyaviruses that cause encephalitis
A
  • all but the choriomeningitis \ ebola and marburg v.
  • la crosse encephalitis
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16
Q

ribavirin is used as a

A

treatment of hentavirus and sin nombre viruses

17
Q
  • horses , australia , respiratory and meningitis and highly fatal
  • pigs , south asia , encephalitis and respiratory and highly fatal mortality
A

hendra virus
nipah virus

18
Q

life cycle of ticks is :

A

ELNA
(egg, larva , nymph , adult )

19
Q

how much does it take to see clinical signs of tick paralysis and where do tick usually bite

A

2- 7 days and starts with weakness of legs then ascending
nick or head

20
Q

ixodes usually causes

A

anaplasmosis , lyme , tbrf , babesiosis, powassan

TB LAP

21
Q

ambylyommma causes :

A

ehrlichiosis , heartland virus, stari, tularemia
SHET

22
Q

Dermacentor causes :

A

colorado tick fever and rocky mountain spotted fever

23
Q

ornithodors cause

A

TBRF tick borne relapsing fever

24
Q

most common type of prion disease in humans is”:

A

sporadic CJD

25
Q

cerebellar syndrome and ataxia are seen in

A

iatrogenic CJD

26
Q

common age for vCJD, accumulates in _____, transmitted by_____.

A

27 years,
lymphoid tissue (tonsils )
surgical instruments and oral and tonsillectomy

27
Q

afflict nervous system via guts,
ph is from 3-9
positive sense ssRNA

A

enterovirus or picornavirus

28
Q

enterovirus. infection is common in ____ and it usually is ____

A

children and asymptomatic

29
Q

post polio syndrome is in surviving cases of paralytic poli and happens after ____

A

20-40years after infection

30
Q

is a polio vaccine thats
used less, have higher risk of vaccination ass diz , lifelong immunity with no need for repeated bosters

A

sabin
live attinuated

31
Q

a polio vaccine thats:
more used, no risk of vaccine ass diz, repeated boosters are needed

A

salk
inactivated or killed

32
Q

type a coxackieviruse causes

A

falccid in mice

aseptuc meningitis, febrile illness,
herpania and HFM (16)

33
Q

type b coxackievirus causes

A

spastic in mice

neonatal diz, myalgia, bornholm diz, myocarditis, pericarditis, hepatiits, meningitis

34
Q

boston fever cause is:

A

parechovirus type 16

35
Q

——: pneumonia & bronchiolitis
——: Not yet associated with clinical diseases
——: acute hemorrhagic conjunctivitis
——: HFM disease (second most common cause)
——: paralysis & meningo-encephalitis
——: hepatitis A → Hepatovirus

A

68 \69 \70 \71 \ 70 & 71 \72

36
Q

main syndrome is paroritis and might cause:
meningitis, orchitis, oophoritis, pancreatitis

A

mumps

37
Q

paramyxovirus vaccine is:

A

MMR (live attenuated)

38
Q

fever, cough, kopliks spots, conjuctivitis are all seen in

its complications can be

A

measles

pneumonia , otitis media, enchephalitism, SSPE

39
Q

most common causes od tick paralysis are

A

dermacentor andersoni and varibils

PNS (6 decks)

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