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Year 5 - Pathology ICSM1 > Microbiology 11 - Viral Hepatitis > Flashcards

Microbiology 11 - Viral Hepatitis Flashcards

1
Q

Recall 2 RFs for Hep A transmission

A
  1. Drinking from dodgy water supply

2. MSM

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2
Q

What is the incubation period for hepatitis A?

A

2-6 weeks

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3
Q

Which immunoglobulin is indicative of current Hep A infection?

A

IgM

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4
Q

Which immunoglobulin is indicative of previous Hep A infection/ vaccine?

A

IgG

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5
Q

What test is used to identify acute hepatitis A?

A

Anti-hepatitis A virus IgM

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6
Q

For how long does hepatitis B infection have to persist to be considered “chronic”?

A

6 months

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7
Q

What is the incubation period for hepatitis B?

A

2-6 months

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8
Q

What are the complications of chronic hepatitis B?

A

Cirrhosis

Hepatocellular carcinoma

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9
Q

Recall the stages of hepatitis B infection

A
  1. Immune tolerant
  2. Immune reactive
  3. Inactive HBV carrier state
  4. HBe antigen negative chronic HBV
  5. HBs antigen negative phase
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10
Q

What treatments are available for chronic hepatitis B?

A

Peg Interferon alpha

NRTIs (Lamivudine, Tenofovir)

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11
Q

What does the hepatitis B vaccine contain?

A

Surface antigen

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12
Q

What are the main routes of transmission of hepatitis C?

A

Blood products

MSM

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13
Q

What % of people who get infected with hepatitis C go on to have chronic hep C?

A

60-80%

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14
Q

What is the incubation period of hepatitis C?

A

2 - 6 weeks

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15
Q

What test is used to diagnose hep C infection?

A

HCV RNA

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16
Q

What treatments are available for hepatitis C?

A

Interferon alpha

NS5B inhibitors

17
Q

Hepatitis D infection is always superimposed upon which type of infection?

A

Hepatitis B

18
Q

Which type of hepatitis only ever takes an acute course?

A

Hepatitis E

19
Q

What is one particularly risky food for hepatitis E infection?

A

Wild boar

20
Q

What are the possible complications of hepatitis E infection?

A

Bell’s palsy

Guillain Barre

Year 5 - Pathology ICSM1 (85 decks)

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