microbiol toxins Flashcards
1
Q
ADP ribosylation
exotoxin A and diptheria toxin
inactivate EF-2 interfering with protein synthesis –> cell death
what bacteria?
A
Pseudomonas aeruginosa
theriaeCorynebacterium dip
2
Q
overactivates adenylate cyclase (inc cAMP) by permanently activating Gs
increasing pumping of Cl- in Gut and H20 efflux
what bateria is responsible
which other bacteria has a similar mech
A
Vibrio cholerae
bordetella has a similiar mech
3
Q
overactivates adenylate cyclase (inc cAMP) by
disabling Gi
impairing phagocytosis to permit survival of microbe.
what microbe?
A
bordetella pertussis
4
Q
vibrio cholera and (ETEC) E coli - enterotoxigenic
use ADP ribosylating A-B toxin to cause?
A
watery diarrhea
5
Q
bordetella pertussis
uses the ADP ribosylating A-B toxins to cause
A
whooping cough and lymphocytosis
6
Q
A
