heme

Question 1

how do you identify hematopoietic stem cell in bone marrow

Answer 1

CD 34

Question 2

immunosuppresed pt waiting for bone marrow transplant

what is the most likely infection?

Answer 2

invasive pulmonary aspergillosis

tx : voriconazole

Question 3

pt with helmeth (t. solium) infection. what does eosinophils secrete to kill this

Answer 3

major basic protein.

Question 4

what should you avoid in HUS

Answer 4

antibiotics

Question 5

target cells in

Answer 5

hemoglobiopathyies (HbC), alcoholic liver disease, asplenia.

Question 6

which anemia will have low TIBC

Answer 6

anemia of chronic disease has low

iron def has high.

Question 7

faconi syndrome (type 2 renal acidosis = proximal tubule)

pt never had serum glucose higher than 80, but he has high glucose in urine

what is the cause

Answer 7

lead poisoning

Question 8

how can INH cause Sideroblastic anemia

Answer 8

inhibits.pyridoxine

Question 9

what are the 4 big causes of sideroblastic anemia

Answer 9

alcohol

pyridoxime B6 def

lead inhibits

lead poisoning

Question 10

what chromosome is B thalassemia on

Answer 10

chromosome 11

Question 11

crw cut appearance

chipmunk facies

hepatosplenomegaly

Answer 11

B thalassemia major.

Question 12

inc risk of gastric malignancy

inc mcv additional autoimmune disorders

Answer 12

pernicious anemia.

Question 13

pt has RA and has been on methotrexate for long time

now has UTI what drug should you avoid

Answer 13

SMX/TMP

bc this also inhibits folate synthesis.

Question 14

plasmapheresis

is treatment for?

Answer 14

TTP

guillain Barre syndrome

Myasthenia gravis

Goodpastures syndrome

hyperviscosity syndrome

- (waldenstrom macroglobulinemia)

Question 16

most common cause of abnormal platelet function?

Answer 16

ASA (aceyl salicylic acid) asprin

not vWF