Microbioal omics Flashcards
genome
the total complement of genetic
information of a cell or a virus
genomics
the discipline that maps,
sequences, analyzes, and compares genomes
bioinformatics
the use of computational
tools to acquire, analyze, store, and access
DNA and protein sequences
sequencing
deducing the order of
nucleotides in a DNA or RNA molecule by a
series of chemical reactions
open reading frames
a sequence of
DNA or RNA that could be translated to give
a polypeptide
codon bias
the relative proportions of
different codons encoding the same amino
acid; it varies in different organisms. Same
as codon usage
transcriptome
the complement of all RNA
produced in an organism under a specific
set of conditions
translatome
the total set of proteins
produced by an organism under a specific
set of conditions
merabolome
the total complement of small
molecules and metabolic intermediates of a
cell or organism
metagenomics
he genomic analysis of
pooled DNA or RNA from an environmental
sample containing organisms that have
metagenome
sm
Metagenome the total genetic complement
of all the cells present in a particular
environment
gene chips
small, solid supports to which
genes or portions of genes are affixed and
arrayed spatially in a known pattern (also
called microarrays)
hybridization
the joining of two singlestranded nucleic acid molecules by
complementary base pairing to form a
double-stranded hybrid DNA or DNA–RNA
molecule
nucleic acid probes
a strand of nucleic
acid that can be used to hybridize with a
complementary strand of nucleic acid in a
mixture; one of the two strands is labeled
proteomics
the genome-wide study of the
structure, function, and regulation of the
proteins of an organism
proteom
(1) the total set of proteins
encoded by a genome or (2) the total
protein complement of an organism under
a given set of conditions, also called the
translatome
interactome
the total set of interactions
between proteins (or other macromolecules)
in an organism
