diagnositcs Flashcards
specificity
the ability of an antibody or a
lymphocyte to recognize a single antigen,
or of a diagnostic test to identify a specific
pathogen
sensitivity
the lowest amount of antigen
that can be detected by a diagnostic test
selective media
ulture media that allow
the growth of certain organisms while
inhibiting the growth of others through
one or more added media components
differential media
a growth media that
allow identification of microorganisms
based on phenotypic properties
minimum inhabitory concentration
the smallest amount of an agent
needed to completely inhibit the growth of
an organism in vitro
serology
the study of antigen–antibody
reactions in vitro
titer
the quantity of a substance, such as
antibody, in a solution
monoclonal antibodies
a single
type of antibody made by a single B cell
hybridoma clone
precipitation
a reaction between antibody
and a soluble antigen resulting in a visible,
insoluble complex
agglutination
a reaction between antibody
and particle-bound antigen resulting in
visible clumping of the particles
fluorescent antibodies
an antibody molecule
covalently modified with a fluorescent
dye that makes the antibody visible under
fluorescent light
enzyme immunoassays
a test that uses
antibodies or antigens linked to enzymes to
detect antigens or antibodies in body fluids
immunoblot
the use
of labeled antibodies to detect specific
proteins after separation by electrophoresis
and transfer to a membrane