Microbio Exam 3 Flashcards
To pass this fucking class lol
What are Gram Positive Cocci?
Staphylococcus
Streptococcus
What are Gram negative Cocci?
Neisseria
Name two features of Staphylococcus
Grapelike clusters
Catalase Positive
Name Two Features of Streptococcus
Chains
Catalase Negative
What is the coagulase positive staphyloccous
S. aureus
What is the coagulase negative Staphylococcus
S. epidermidis
S. saprophyticus
What can S. Aureus cause
Folliculitis
Furuncle
Carbuncle
Impegito
What else can Staphylococcus cause?
Toxigenic diseases such as food intoxication, staphylococcal scaled skin syndrome, and toxic shock syndrome
What toxin induces bright red flush, blisters, then slow decaudation of the epidermis
Exfoliation Toxin
Toxemia leading to shock and organ failure is called
Toxic Shock Syndrome
What is the almost always nosocomial normal flora that only causes diseases when it enters the bloodstream
S. epidermidis
What is the almost always community acquired UTI in young, sexually active women?
Staphylococcus/S. Saprophyticus
What are the classification systems based on the cell walls and the systems based on how it affects the blood
First system is called Lancefield classification, Second system is called hemolysis
What is hemolysis?
Hemolysis is a classification of how a gram-positive bacteria affects the bloodstream based on how well it eradicates/limits RBC function
What are the B bacteria hemolysis capable of?
Breaking down red blood cells, eliminating them entirely
What are A hemolysis bacteria capable of?
Partial and incomplete breakdown red blood cells, turning them green
S pyogenes is a
Group A-Beta
S. agalactiae is a
Group B-Beta
S. pneumoniae
N/A - Alpha
The important virulence factor in streptococcus pyogenes
M-Protein
What facilitates the spread of streptococcus through tissues
Hyaluronidase
What can stimulate fever, rash, and shock?
Pyrogenic toxins
What causes superficial lesions to break and form highly contagious crust; often in epidemics in school children
Impetigo
What is Streptococcal pharyngitis
Strep Throat
What are other diseases caused by S. pyogenes (there are four)
Scarlet Fever, Septicemia
Pneumonia, Streptococcal toxic shock syndrome
What follows overt or subclinical pharyngitis in children, causing extensive valve damage in the heart?
Rheumatic fever
What is the long term complication of Group A infections that can cause kidney damage and could become chronic?
Acute glomerulonephritis
What is the exotoxin that is a superantigen that causes dissolving skin tissue?
Necrotizing fasciits
What is the only group B disease that regularly resides in human vagina and is only serious in pregnant women?
Streptococcus agalactiae
What is the most serious infection of alpha-hemolysis streptococci that affects the heart
Subacute endocarditis
What causes plaque on teeth
Streptococcus mutans
What causes 60-70% of all bacterial pneumonias as well as meningitis
Streptococcus pneumoniae
What are the two gram negative cocci human pathogens
Neisseria gonorrhoeae
Neisseria meningitidis
What are the virulence factors of gonorrhea (two)
Fimbriae and an IgA protease
What causes gonorrhea
Neisseria gonorrhoeae
What causes yellowish discharge, scarring and infertility in men affected by gonorrhea
Urethritis
What are the virulence factors for Neisseria meningitis
capsules, adhesive fimbriae, IgA protease, endotoxins
What are the medically important gram positive bacilli? (four)
Bacillus
Crostridium
Corynebacterium
Listeria
What are the endospore forming bacilli (Two)
Bacillus
Clostridium
What is the dense survival unit that develops in a vegetative cell in response to nutrient depravation or other unfavorable conditions?
endospore
What are some general characteristics of Bacillus
Gram Positive
Endospore Forming
Rods
Mostly Saprobic
Aerobic, facultative anaerobes
Primary habitat is soil
What are the two species of medical importance in Bacillus and what is the motility of them?
Anthracis - nonmotile
Cereus - Motile
What are the four types of Anthrax?
Cutaneous
Gastrointestinal
Pulmonary
Injectional
What is Bacillus cereus most commonly associated with
foods, mainly rice that is undercooked
What are some general characteristics of clostridium
Gram Positive
Forms endospores
Anaerobic (dies in presence of oxygen)
Synthesize organic acids, alcohols, exotoxins
What is the most frequent clostridium involved in soft tissue and would infections
Clostridium perfringens
What is the localized death of muscle cell fibers caused by clostridium perfringens
Myonecrosis
What is the removal of diseased tissue / myonecrosis
Debridement
What causes tetanus or lockjaw
Clostridium tetani
What causes c-dif, a disease that produces the exotoxin that damages intestines
Clostridium difficile
What is the intoxication associated with inadequate food preservation?
Botulism
What is the spore-forming anaerobe, commonly inhabiting soil and water
Clostridium Botulinum
What happens when spores enter wound and cause food poisoning symptoms
Wound botulism
What are non-spore forming gram-positive bacteria that are resistant to cold, heat, salt, ph extremes, and biles
Listeria monocytogenes
What is caused by association with dairy products, poultry, and meat
Listeriosis
What causes Diphtheroid, a very serious respiratory condition
Corynebacterium Diphtheriae
What are the two stages of Diphtheria
- Local infection in the upper respiratory tract infection (primary infection)
- Diphtherotoxin production and toxemia, Targeting heart and nerves
What are the general characteristics of Mycobacterium
Gram-positive
acid-fast
Irregular bacteria
Strict Aerobes
Produce Catalase (reduces hydrogen peroxide)
Mycobacterium is a _______
Acid-Fast Bacilli
What are the clinical methods of detecting TB (tuberculosis)
- Tuberculin sensitivity (Mantoux test)
In vireo TB test
Chest x-ray
Acid-fast Staining
Cultural isolation and biochemical testing
What causes leprosy/Hansen’s diseases
Mycobacterium leprae
What is the cause of dissimilated mycobacterial infection in aids
Mycobacterium avium complex bacilli
What are the two forms of leprosis?
Tuberculoid
Lepromatous
What causes Bacilli ulcers
Mycobacterium ulcerans
What causes turberculosis
Mycobacterium tuberculosis
pseudomonas is a _______ pathogen
opportunistic
Brucella and Francisella are _____ pathogens
zoonotic
Bordetella and Legionella are ______ pathogens
(mainly) human
What are some characteristics of Pseudomonas aeruginosa
Common cause of nosocomial (hospital-borne) infections in hosts with burns, neoplastic disease, cystic fibrosis that causes complications such as pneumonia, UTI, abscesses, otitis, and corneal disease. Multidrug resistant and grapelike odor.
What causes tularemia, a zoonotic disease of mammals endemic to rabbits and primary vector is ticks?
Francisella tularensis
What causes pertussis or whooping cough, and what is the reservoir and transmission?
Bordetella pertussis
reservoir - humans
Transmission - Direct contact or inhalation of aerosols
What are the virulence factors of Bordetella pertussis
-Receptors that recognize and bind to ciliated respiratory epithelial cells
Toxins that destroy and dislodge ciliated cells lead to buildup of mucus and blockage of airways
What are the three stages of Bordetella pertussis
- Catarrhal stage (common cold)
- Paroxysmal stage - Violent coughing sieges
- Convalescence stage
What is the disease widely distributed in water, in close association with amoebas that has men at +50 at high risk (especially those in the HVAC industry)
Legionella pneumophila
What are coliforms?
lactose fermenters
The meaning of H is
flagellar antigen
The meaning of K is
Capsule and/or fimbrial antigen
The meaning of O is
The somatic or cell wall antigen
Not all species carry ______ or _____ antigens but all have ____
Not - H or K
All - O
E-Coli causes
70%~ of traveler’s diarrhea
50-60% of UTIs
What inhabit of respiration tract that has a large capsule, cause of nosocomial pneumonia, meningitis, bacteremia, wound infection, UTI and is opportunistic as well as drug-resistant
Klebsiella pneumoniae
What are the two true enteric pathogens
Salmonellooses and Shigelloses
Typhoid fever is caused by _____ with ____ reservoir and _____ transmission
Salmonella typhi, human, fecal-oral
Salmonellosis other than typhoid fever are called
Enteric fever
Salmonella enteritis is all _______ in origin but ____ can become carriers
Zoonotic in nature but humans can become carriers
What is the common incapacitating dysentery
Shigellosis
What caused the plague
Yersinia pestis
What is humans developing plague through contact with wild animals
Sylvatic plague
Urban plague is
Developing the plague through contact (human contact?)
hemophiles is ______ loving
blood
What causes acute bacterial meningitis
H. influenzae
What is the chancroid, soft chance STI that requires factor X
H. ducreyi
What are the features of spirochetes
Gram-negative human pathogens
Free living saprobes, commensal of animals
Not primary pathogens
What are three of the spirochete genus (that we cover)
treponema
Leptospira
Borrelia
What is the cause of Syphilis, and what is the reservoir
Treponema pallidum
human reservoir
What are some features of leptospirosis
Tiny, regular individual coils will bend or hook at one or both ends
What are leptosomatic, a zoonosis disease
Leptospira interorgan
What causes lyme disease
B. burgdorferi
How is B. burgdorferi/Lyme disease transmitted?
through ticks
What are the comma-shaped rods with single polar flagellum
Vibrio
What is the spirochete with tight spirals and several polar flagella
Helicobacter
what is the gastroenteritis from raw seafood
Vibrio parahaemolyticus
What is the gastroenteritis from raw oysters
Vibrio vulnificus
What is the gastric pathogen that produces urease which coverts urea into ammonium and bicarbonate
Helicobacter pylori
The intracellular pathogen that rely on arthropod vector are called
Rickettsia
The intracellular pathogens that alternate between elementary and reticulate bodies is called
Chlamydia
what lacks a cell wall and are highly pleomorphic
Mycoplasma
What is the cause and vector epidemic typhus
R. prowazekii
Vector - Lice
What is the cause and vector of endemic typhus
R. typhi
Vector - Flea
What causes rocky mountain settled fever and what is the vector
R. rickettsii
Vector - Ticks
What is the agent of cat-scratch disease
Bartonella_henselae
What is the Lancefield classification based on?
Cell wall
What is the severe case of Tetanus caused primarily in people with a large amount of muscle mass?
Opisthotonos
The release of toxins during __________ may cause hemorrhage, coagulation, and vascular damage, leading to necrosis of tissue especially in the extremities
meningococcemia
Woolsorter’s disease is
Bacillus anthracist / anthrax