Microbial growth Pathogens

Question 1

Corynebacterium diphtheriae stain ?

Answer 1

Gram (+) rod

Question 2

Corynebacterium dipheriae optimum growth ?

Answer 2

37

Mesophile

Question 3

Corynebacterium diphtheriae causes?

Answer 3

Diphtheria

Question 4

Diphtheriae transmission

Answer 4

Droplet

Question 5

Corynebacterium diphtheriae pathogenesis

Answer 5

Colonize nose/ throat—> back of throat
Produces diphtheriae toxin: prevents protein synthesis—> cell death
Dead tissue forms a thick coating- pseudomembrane
Composed of dead cells, Corynebacterium diphtheriae, white blood cells, and fibrin

Question 6

Diphtheria signs/symptoms

Answer 6

Fever 
Sore throat 
Pseudomembrane
White —> gray, green, or black 
Swollen neck

Question 7

Diphtheria Dx

Answer 7

Culture

Question 8

Diphtheria Tx

Answer 8

Erythromycin

Diphtheria antitoxin

Question 9

Campylobacter jejuni Gram stain

Answer 9

Gram (-) spiral

Question 10

Campylobacter jejuni temperature classes

Answer 10

Microaerophile

Capnophile

Question 11

Campylobacter jejuni causes

Answer 11

Campylobacteriosis

Question 12

Campylobacteriosis transmission

Answer 12

Foodborne

Question 13

Campylobacter jejuni pathogenesis ?

Answer 13

Invades intestinal epithelial layer
Helped by flagella and capsule
Produces toxins: stop cell growth —> damage
intestinal cells

Question 14

Campylobacteriosis signs/symptoms

Answer 14

Diarrhea, fever, ab. cramps, N/V/D

Question 15

Campylobacteriosis Dx

Answer 15

Culture

Question 16

Campylobacter Tx:

Answer 16

Fluids

Antibio in severe cases

Question 17

Clostridium perfringens stain

Answer 17

Gram (+) rod

Question 18

Clostridium perfringens classification

Answer 18

Obligate anaerobes

Can form endospores

Question 19

Clostridium perfringens causes ?

Answer 19

Food poisoning

Gas gangrene

Question 20

Clostridium perfringens Trans ?

Answer 20

Foodborne

Question 21

Clostridium perfringens gastroenteritis pathogenesis

Answer 21

colonizes intestinal tract

Produces Clostridium perfringens enterotoxin -> forms pores in intestinal cells—> cell death

Question 22

Clostridium perfringens gastroenteritis signs/symptoms

Answer 22

Diarrhea and abd, pain

Question 23

Clostridium Perfringens gastroenteritis Dx/Tx

Answer 23

Usually self limiting

Question 24

Gangrene is ?

Answer 24

Soft tissue death

Question 25

Gangrene results from ?

Answer 25

Loss of blood supply

Anaerobic

Question 26

In gangrene dying cells are release substance that cab be ?

Answer 26

Used as nutrient by bacteria

Question 27

Gas gangrene Transmission

Answer 27

Usually from contamination of surgical site

Question 28

Gas gangrene pathogenesis

Answer 28

Clostridium perfringens grows in tissues with
low O2

C. perfringens ferment carbohydrates —> gas
—> tissue swelling

C. perfringens produces toxins that kill cells
->necrotic tissue—more space for C.
perfringens to grow

Question 29

Gas gangrene signs/symptoms

Answer 29

Redness/swelling
Severe pain or loss of sensation
Cold/pale skin
Bubbling/blisters

Question 30

Gas gangrene Dx

Answer 30

XRay

Culture

Question 31

Gas gangrene Tx

Answer 31

Clindamycin
Surgical removal of necrotic tissue
Amputation