Fungi pathogens

Question 1

What is the normal flora of intestinal tract mouth and vagina

Answer 1

Cándida albicans

Question 2

Cándida albicans causes

Answer 2

Candidiasis

Question 3

Types of candidiasis

Answer 3

Candidiasis of the mouth, throat, and esophagus
Vaginal candidiasis
Invasive candidiasis

Question 4

Candida albicans Pathogenesis

Answer 4

Dimorphic
Yeast: attachment and dissemination
Hyphae: invasion of host tissue 
Candida albicans (yeast) adhere to host
cells 
Candida albicans yeast germinate hyphae
further spread 
Can form biofilms on host tissue

Question 5

Candidiasis of the Mouth, Throat, and Esophagus

Causes

Answer 5

change in mouth, throat, or esophagus that

favors Candida albicans growth

Question 6

Candidiasis of the Mouth, Throat, and Esophagus

Types

Answer 6

Thrush: candidiasis in mouth or throat Esophageal candidiasis: in esophagus

Question 7

Candidiasis of the Mouth, Throat, and Esophagus

Symptoms

Answer 7

White patches on cheeks, tongue, roof of mouth, or throat
Redness/soreness
Pain while eating/swallowing

Question 8

Vaginal Candidiasis causes

Answer 8

vaginal environment changes to favor

Candida albicans growth

Question 9

Vaginal Candidiasis signs

Answer 9

Vaginal itching
Painful urination
Discharge

Question 10

Invasive Candidiasis causes

Answer 10

Candida albicans enter blood

Question 11

Invasive Candidiasis signs

Answer 11

Fever & chills

Question 12

Candidiasis Diagnosis/Treatment Dx

Answer 12

Microscopy

Culture

Question 13

Candidiasis Tx

Answer 13

Azole antifungals

Echinocandins

Question 14

Basidiomycota

Edible

Answer 14

Boletus, Shitake

Question 15

Basidiomycota

Hallucinogenic

Answer 15

Psilocybe

Contains psilocybin —>psilocin —>binds to serotonin receptors

Question 16

Basidiomycota Human pathogen

Answer 16

Amanita phalloides

Question 17

Amanita phalloides is

Answer 17

Death cap mushroom

Question 18

Amanita phalloides

Pathogenesis

Answer 18

Produces amatoxins: stop protein

synthesis —>cell death

Question 19

Amanita phalloides Signs/symptoms

Answer 19

Stomach pains, vomiting, diarrhea
Easing of symptoms
Return of stomach pains, vomiting, diarrhea + jaundice

Question 20

Amanita phalloides

Tx

Answer 20

Rehydration, possible liver transplant

Question 21

Ascomycota is

Answer 21

Sac fungi

Question 22

Ascomycota cause mycoses

Answer 22

Cutaneous mycoses

Stachybotrys infections

Question 23

Cutaneous Mycoses

Answer 23

Fungal infections of the hair, nails, skin

Question 24

Cutaneous Mycoses

Answer 24

Genera involved:
Trichophyton
Microsporum
Epidermophyton

Question 25

An example of Cutaneous Mycoses

Answer 25

Ringworm

Question 26

Ringworm sign/symptoms

Answer 26

Itchy red circular rash

Question 27

Ringworm types

Answer 27

Types:
Tinea capitis: scalp
Tinea cruris: groin (jock itch)
Tinea pedis: feet (athlete’s foot)

Question 28

Ringworm etiológicas agents

Answer 28

Trichophyton, Microsporum,Epidermophyton species

Question 29

Ringworm transmission:

Answer 29

Direct contact
People/animals
Can spread from one part of the body to another
Fomites

Question 30

Ringworm signs/symptoms

Answer 30

Tinea capitis: scaly, itchy, red, circular bald spot
Tinea cruris: scaly, itchy, red spots on skin folds of thigh
Tinea pedis: red, peeling, itchy skin on feet

Question 31

Ringworm Dx

Answer 31

Microscopy

Question 32

Ringworm tax

Answer 32

Azole antfungals

Question 33

Stachybotrys chartarum

Answer 33

“Black Mold”
Found outdoors
Can grow in buildings(Moisture required )

Question 34

Stachybotrys chartarum

Tx

Answer 34

inhalation of spores

Question 35

Stachybotrys chartarum pathogenesis pathogenesis

Answer 35

produce mycotoxins and
immunosuppressive agents
Mycotoxins inhibit protein synthesis

Question 36

Stachybotrys chartarum

Signs/symptoms

Answer 36

Allergic reactions
Headache, fever, muscle aches
Memory loss/difficulty concentrating