Microbial Control In The Environment Flashcards

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1
Q

Drugs

A

Chemicals that affect physiology in any manner

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2
Q

Chemotherapeutic agents

A

Drugs that act against diseases

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3
Q

Antimicrobral agents

A

Drugs that treat infections

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4
Q

Antibiotics

A

Antimicrobial agents that are produced naturally by an organism

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5
Q

Semisynthetic antimicrobials

A

Chemically altered antibiotics

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6
Q

Synthetic antimicrobials

A

Lab-synthesized antimicrobral drugs

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7
Q

Spectrum of action

A

Number of different pathogens a drug acts against

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8
Q

Narrow-spectrum

A

Effective against few organisms

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9
Q

Broad-spectrum

A

Effective against many organisms

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10
Q

Routes of administration

A

Topical, oral intramuscular, intravenous

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11
Q

Disruption of normal microbiota

A

May result in secondary infections, overgrowth of normal flora causing secondary infections, of greatest concern for hospitalized patients

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12
Q

CDC three threat levels for microbial resistance

A

Urgent, serious, and concerning

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13
Q

Urgent

A

Potential for widespread life threatening disease

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14
Q

Serious

A

Alternative available or disease incidence is low or declining

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15
Q

Concerning

A

Low threat or numerous antimicrobials are available for treatment

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16
Q

Synergism

A

Occurs when one drug enhances the effect of a second drug

17
Q

Antagonism

A

Occurs when drugs interfere with each other

18
Q

Persister

A

Cells with the same genome as others of the same species, but that display greater resistance to antimicrobial agents

19
Q

Pieces of dna, not apart of the normal chromosome, that give the bacteria antimicrobial resistance properties

A

R plasmids

20
Q

The ratio of the dose of a drug that can be tolerated compared with the drugs effective dosage

A

Therapeutic index

21
Q

Proteins made by bacteria to inhibit or kill other bacteria that may be copied in a lab to produce medications

A

Bacteriotocins

22
Q

When multiple drugs are similar in structure or function a pathogen may be resistant to both. This is

A

Cross resistance