microbes in oral health and disease Flashcards
what promotes the balance of disease in our favour?
Immune system
Vaccines
Antimicrobial agents
what promotes the balance of disease against our favour?
Immuno-supression
Virulence factors
Resistance
what are the main contributors to oral health?
- integrity of oral mucosa
- lymphoid tissue
- saliva
- gingival crevicular fluid
- humoral and cellular immunity
innate immune system
- barriers
- non-specific cellular
- inflammation
acquired immune system
- specific
- memory
- T cels and B cells
what are the antimicrobial actions of saliva?
- mechanical cleansing
- lysozyme
- peroxidase
- lactoferrin
- leucocytes
- secretory IgA
what is the ubiquitous meaning of bacteria?
lives in multiple environments
what does it mean that bacteria is diverse?
variety of shapes, sizes and characteristics
what does it mean that bacteria is adaptable?
evolves quickly
what are virulence factors?
the molecules that assist the bacterium colonise the host at the cellular level
what are examples of virulence factors?
Motility- Flagella
Adhesion- Pili/Fimbriae
Colonisation- Extrapolymeric material
Invasion- Enzymes/toxins
Spread- Immune evasion
what do pili help bacteria do?
stick- difficult to remove
what causes oral disease?
alterations in microbial flora
what are the factors which give dental caries?
- plaque microorganisms
- diet (sugar)
- time
- teeth
what is endodontic infection?
- infected pulp
- secondary to tooth infection/trauma
- derived from endogenous microflora
